Duan W - Search Results

1

An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models.

Morelli KH, Wu Q, Gosztyla ML, Liu H, Yao M, Zhang C, Chen J, Marina RJ, Lee K, Jones KL, Huang MY, Li A, Smith-Geater C, Thompson LM, Duan W, Yeo GW. Morelli KH, et al. Among authors: duan w. Nat Neurosci. 2023 Jan;26(1):27-38. doi: 10.1038/s41593-022-01207-1. Epub 2022 Dec 12. Nat Neurosci. 2023. PMID: 36510111 Free PMC article.

2

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.

Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, Zhang J, Mori S, Yang XW, Tamashiro KL, Aja S, Moran TH, Luthi-Carter R, Martin B, Maudsley S, Mattson MP, Cichewicz RH, Ross CA, Holtzman DM, Krainc D, Duan W. Jiang M, et al. Among authors: duan w. Nat Med. 2011 Dec 18;18(1):153-8. doi: 10.1038/nm.2558. Nat Med. 2011. PMID: 22179319 Free PMC article.

3

Mutant Huntingtin Disrupts the Nuclear Pore Complex.

Grima JC, Daigle JG, Arbez N, Cunningham KC, Zhang K, Ochaba J, Geater C, Morozko E, Stocksdale J, Glatzer JC, Pham JT, Ahmed I, Peng Q, Wadhwa H, Pletnikova O, Troncoso JC, Duan W, Snyder SH, Ranum LPW, Thompson LM, Lloyd TE, Ross CA, Rothstein JD. Grima JC, et al. Among authors: duan w. Neuron. 2017 Apr 5;94(1):93-107.e6. doi: 10.1016/j.neuron.2017.03.023. Neuron. 2017. PMID: 28384479 Free PMC article.

4

Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.

Jiang M, Zhang X, Liu H, LeBron J, Alexandris A, Peng Q, Gu H, Yang F, Li Y, Wang R, Hou Z, Arbez N, Ren Q, Dong JL, Whela E, Wang R, Ratovitski T, Troncoso JC, Mori S, Ross CA, Lim J, Duan W. Jiang M, et al. Among authors: duan w. Hum Mol Genet. 2020 May 28;29(8):1340-1352. doi: 10.1093/hmg/ddaa061. Hum Mol Genet. 2020. PMID: 32242231 Free PMC article.

5

Abnormal Brain Development in Huntington' Disease Is Recapitulated in the zQ175 Knock-In Mouse Model.

Zhang C, Wu Q, Liu H, Cheng L, Hou Z, Mori S, Hua J, Ross CA, Zhang J, Nopoulos PC, Duan W. Zhang C, et al. Among authors: duan w. Cereb Cortex Commun. 2020;1(1):tgaa044. doi: 10.1093/texcom/tgaa044. Epub 2020 Aug 5. Cereb Cortex Commun. 2020. PMID: 32984817 Free PMC article.

6

Development of novel bioassays to detect soluble and aggregated Huntingtin proteins on three technology platforms.

Landles C, Milton RE, Jean A, McLarnon S, McAteer SJ, Taxy BA, Osborne GF, Zhang C, Duan W, Howland D, Bates GP. Landles C, et al. Among authors: duan w. Brain Commun. 2021 Jan 5;3(1):fcaa231. doi: 10.1093/braincomms/fcaa231. eCollection 2021. Brain Commun. 2021. PMID: 33604571 Free PMC article.

7

Huntingtin silencing delays onset and slows progression of Huntington's disease: a biomarker study.

Liu H, Zhang C, Xu J, Jin J, Cheng L, Miao X, Wu Q, Wei Z, Liu P, Lu H, van Zijl PCM, Ross CA, Hua J, Duan W. Liu H, et al. Among authors: duan w. Brain. 2021 Nov 29;144(10):3101-3113. doi: 10.1093/brain/awab190. Brain. 2021. PMID: 34043007 Free PMC article.

8

Age-dependent cerebrospinal fluid-tissue water exchange detected by magnetization transfer indirect spin labeling MRI.

Li AM, Chen L, Liu H, Li Y, Duan W, Xu J. Li AM, et al. Among authors: duan w. Magn Reson Med. 2022 May;87(5):2287-2298. doi: 10.1002/mrm.29137. Epub 2021 Dec 27. Magn Reson Med. 2022. PMID: 34958518 Free PMC article.

9

Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches.

Smith EJ, Sathasivam K, Landles C, Osborne GF, Mason MA, Gomez-Paredes C, Taxy BA, Milton RE, Ast A, Schindler F, Zhang C, Duan W, Wanker EE, Bates GP. Smith EJ, et al. Among authors: duan w. Brain Commun. 2023 Jan 20;5(1):fcad010. doi: 10.1093/braincomms/fcad010. eCollection 2023. Brain Commun. 2023. PMID: 36756307 Free PMC article.

10

Interrogation of dynamic glucose-enhanced MRI and fluorescence-based imaging reveals a perturbed glymphatic network in Huntington's disease.

Liu H, Chen L, Zhang C, Liu C, Li Y, Cheng L, Wei Z, Zhang Z, Lu H, van Zijl PCM, Iliff JJ, Xu J, Duan W. Liu H, et al. Among authors: duan w. bioRxiv [Preprint]. 2023 Apr 3:2023.04.03.535397. doi: 10.1101/2023.04.03.535397. bioRxiv. 2023. PMID: 37066166 Free PMC article. Preprint.

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