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Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.
Jiang M, Zhang X, Liu H, LeBron J, Alexandris A, Peng Q, Gu H, Yang F, Li Y, Wang R, Hou Z, Arbez N, Ren Q, Dong JL, Whela E, Wang R, Ratovitski T, Troncoso JC, Mori S, Ross CA, Lim J, Duan W. Jiang M, et al. Among authors: liu h. Hum Mol Genet. 2020 May 28;29(8):1340-1352. doi: 10.1093/hmg/ddaa061. Hum Mol Genet. 2020. PMID: 32242231 Free PMC article.
Glymphatic influx and clearance are perturbed in Huntington's disease.
Liu H, Chen L, Zhang C, Liu C, Li Y, Cheng L, Ouyang Y, Rutledge C, Anderson J, Wei Z, Zhang Z, Lu H, van Zijl PC, Iliff JJ, Xu J, Duan W. Liu H, et al. Among authors: liu c. JCI Insight. 2024 Oct 22;9(20):e172286. doi: 10.1172/jci.insight.172286. JCI Insight. 2024. PMID: 39226105 Free PMC article.
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