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Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome.
Dinstag G, Shulman ED, Elis E, Ben-Zvi DS, Tirosh O, Maimon E, Meilijson I, Elalouf E, Temkin B, Vitkovsky P, Schiff E, Hoang DT, Sinha S, Nair NU, Lee JS, Schäffer AA, Ronai Z, Juric D, Apolo AB, Dahut WL, Lipkowitz S, Berger R, Kurzrock R, Papanicolau-Sengos A, Karzai F, Gilbert MR, Aldape K, Rajagopal PS, Beker T, Ruppin E, Aharonov R. Dinstag G, et al. Among authors: rajagopal ps. Med. 2023 Jan 13;4(1):15-30.e8. doi: 10.1016/j.medj.2022.11.001. Epub 2022 Dec 12. Med. 2023. PMID: 36513065 Free PMC article.
Sex Biases in Cancer and Autoimmune Disease Incidence Are Strongly Positively Correlated with Mitochondrial Gene Expression across Human Tissues.
Crawford DR, Sinha S, Nair NU, Ryan BM, Barnholtz-Sloan JS, Mount SM, Erez A, Aldape K, Castle PE, Rajagopal PS, Day CP, Schäffer AA, Ruppin E. Crawford DR, et al. Among authors: rajagopal ps. Cancers (Basel). 2022 Nov 29;14(23):5885. doi: 10.3390/cancers14235885. Cancers (Basel). 2022. PMID: 36497367 Free PMC article.
Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissues.
Sanghvi N, Calvo-Alcañiz C, Rajagopal PS, Scalera S, Canu V, Sinha S, Schischlik F, Wang K, Madan S, Shulman E, Papanicolau-Sengos A, Blandino G, Ruppin E, Nair NU. Sanghvi N, et al. Among authors: rajagopal ps. bioRxiv [Preprint]. 2023 Nov 2:2023.10.30.564810. doi: 10.1101/2023.10.30.564810. bioRxiv. 2023. Update in: Sci Adv. 2024 Dec 6;10(49):eadn0220. doi: 10.1126/sciadv.adn0220 PMID: 38076973 Free PMC article. Updated. Preprint.
Outcome differences by sex in oncology clinical trials.
Kammula AV, Schäffer AA, Rajagopal PS, Kurzrock R, Ruppin E. Kammula AV, et al. Among authors: rajagopal ps. Nat Commun. 2024 Mar 23;15(1):2608. doi: 10.1038/s41467-024-46945-x. Nat Commun. 2024. PMID: 38521835 Free PMC article.
The expression patterns of different cell types and their interactions in the tumor microenvironment are predictive of breast cancer patient response to neoadjuvant chemotherapy.
Dhruba SR, Sahni S, Wang B, Wu D, Rajagopal PS, Schmidt Y, Shulman ED, Sinha S, Sammut SJ, Caldas C, Wang K, Ruppin E. Dhruba SR, et al. Among authors: rajagopal ps. bioRxiv [Preprint]. 2024 Jun 14:2024.06.14.598770. doi: 10.1101/2024.06.14.598770. bioRxiv. 2024. PMID: 39372749 Free PMC article. Preprint.
Network-based approach elucidates critical genes in BRCA subtypes and chemotherapy response in Triple Negative Breast Cancer.
Agrawal P, Jain N, Gopalan V, Timon A, Singh A, Rajagopal PS, Hannenhalli S. Agrawal P, et al. Among authors: rajagopal ps. bioRxiv [Preprint]. 2023 May 23:2023.05.21.541618. doi: 10.1101/2023.05.21.541618. bioRxiv. 2023. Update in: iScience. 2024 Apr 16;27(5):109752. doi: 10.1016/j.isci.2024.109752 PMID: 37425784 Free PMC article. Updated. Preprint.
Refining Our Relationship to Cancer With Both Alleles.
Rajagopal PS. Rajagopal PS. JAMA Netw Open. 2025 Jan 2;8(1):e2451303. doi: 10.1001/jamanetworkopen.2024.51303. JAMA Netw Open. 2025. PMID: 39745708 Free article. No abstract available.
34 results