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Page 1
Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.
O'Meara TR, Nanishi E, McGrath ME, Barman S, Dong D, Dillen C, Menon M, Seo HS, Dhe-Paganon S, Ernst RK, Levy O, Frieman MB, Dowling DJ. O'Meara TR, et al. Among authors: dillen c. bioRxiv [Preprint]. 2022 Dec 7:2022.12.07.519460. doi: 10.1101/2022.12.07.519460. bioRxiv. 2022. Update in: J Allergy Clin Immunol. 2023 Nov;152(5):1107-1120.e6. doi: 10.1016/j.jaci.2023.06.031 PMID: 36523401 Free PMC article. Updated. Preprint.
Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity.
Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Brook B, Chen J, Diray-Arce J, Doss-Gollin S, Leon M, Chew K, Menon M, Song K, Xu AZ, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Sherman AC, Baden LR, Ernst RK, Dillen C, Weston SM, Johnson RM, Hammond HL, Mayer R, Burke A, Bottazzi ME, Hotez PJ, Strych U, Chang A, Yu J, Barouch DH, Dhe-Paganon S, Zanoni I, Ozonoff A, Frieman MB, Levy O, Dowling DJ. Nanishi E, et al. Among authors: dillen c. bioRxiv [Preprint]. 2021 May 21:2021.05.20.444848. doi: 10.1101/2021.05.20.444848. bioRxiv. 2021. Update in: Sci Transl Med. 2022 Jan 26;14(629):eabj5305. doi: 10.1126/scitranslmed.abj5305 PMID: 34031655 Free PMC article. Updated. Preprint.
Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection.
Schultz DC, Johnson RM, Ayyanathan K, Miller J, Whig K, Kamalia B, Dittmar M, Weston S, Hammond HL, Dillen C, Castellana L, Lee JS, Li M, Lee E, Constant S, Ferrer M, Thaiss CA, Frieman MB, Cherry S. Schultz DC, et al. Among authors: dillen c. bioRxiv [Preprint]. 2021 Jun 24:2021.06.24.449811. doi: 10.1101/2021.06.24.449811. bioRxiv. 2021. Update in: Nature. 2022 Apr;604(7904):134-140. doi: 10.1038/s41586-022-04482-x PMID: 34189531 Free PMC article. Updated. Preprint.
SARS-CoV-2 Variant Spike and accessory gene mutations alter pathogenesis.
McGrath ME, Xue Y, Dillen C, Oldfield L, Assad-Garcia N, Zaveri J, Singh N, Baracco L, Taylor L, Vashee S, Frieman M. McGrath ME, et al. Among authors: dillen c. bioRxiv [Preprint]. 2022 Jun 1:2022.05.31.494211. doi: 10.1101/2022.05.31.494211. bioRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2204717119. doi: 10.1073/pnas.2204717119 PMID: 35677080 Free PMC article. Updated. Preprint.
Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2.
Johnson R, Ardunay J, Hammond H, Logue J, Jackson L, Baracco L, McGrath M, Dillen C, Patel N, Smith G, Frieman M. Johnson R, et al. Among authors: dillen c. bioRxiv [Preprint]. 2023 May 5:2022.10.15.512291. doi: 10.1101/2022.10.15.512291. bioRxiv. 2023. Update in: J Virol. 2023 Nov 30;97(11):e0133623. doi: 10.1128/jvi.01336-23 PMID: 36299426 Free PMC article. Updated. Preprint.
SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression.
McGrath ME, Xue Y, Taylor L, Dillen C, Ardanuy J, Gonzalez-Juarbe N, Baracco L, Kim R, Hart R, Assad-Garcia N, Vashee S, Frieman MB. McGrath ME, et al. Among authors: dillen c. PLoS Pathog. 2024 May 23;20(5):e1011669. doi: 10.1371/journal.ppat.1011669. eCollection 2024 May. PLoS Pathog. 2024. PMID: 38781259 Free PMC article.
A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice.
Case JB, Sanapala S, Dillen C, Rhodes V, Zmasek C, Chicz TM, Switzer CE, Scheaffer SM, Georgiev G, Jacob-Dolan C, Hauser BM, Dos Anjos DCC, Adams LJ, Soudani N, Liang CY, Ying B, McNamara RP, Scheuermann RH, Boon ACM, Fremont DH, Whelan SPJ, Schmidt AG, Sette A, Grifoni A, Frieman MB, Diamond MS. Case JB, et al. Among authors: dillen c. Cell Host Microbe. 2024 Dec 11;32(12):2131-2147.e8. doi: 10.1016/j.chom.2024.10.016. Epub 2024 Nov 18. Cell Host Microbe. 2024. PMID: 39561781 Free article.
Efficacy and Safety of Abrocitinib in Prurigo Nodularis and Chronic Pruritus of Unknown Origin: A Nonrandomized Controlled Trial.
Kwatra SG, Bordeaux ZA, Parthasarathy V, Kollhoff AL, Alajmi A, Pritchard T, Cornman HL, Kambala A, Lee KK, Manjunath J, Ma EZ, Dillen C, Kwatra MM. Kwatra SG, et al. Among authors: dillen c. JAMA Dermatol. 2024 Jul 1;160(7):717-724. doi: 10.1001/jamadermatol.2024.1464. JAMA Dermatol. 2024. PMID: 38837144 Free PMC article. Clinical Trial.
99 results