Desmet N - Search Results

1

Structural investigation of human cystine/glutamate antiporter system x_c ^- (Sx_c ^-) using homology modeling and molecular dynamics.

Hang TD, Hung HM, Beckers P, Desmet N, Lamrani M, Massie A, Hermans E, Vanommeslaeghe K. Hang TD, et al. Among authors: desmet n. Front Mol Biosci. 2022 Dec 1;9:1064199. doi: 10.3389/fmolb.2022.1064199. eCollection 2022. Front Mol Biosci. 2022. PMID: 36533083 Free PMC article.

2

Differential regulation of glutamate transporter subtypes by pro-inflammatory cytokine TNF-α in cortical astrocytes from a rat model of amyotrophic lateral sclerosis.

Dumont AO, Goursaud S, Desmet N, Hermans E. Dumont AO, et al. Among authors: desmet n. PLoS One. 2014 May 16;9(5):e97649. doi: 10.1371/journal.pone.0097649. eCollection 2014. PLoS One. 2014. PMID: 24836816 Free PMC article.

3

The anti-inflammatory peptide stearyl-norleucine-VIP delays disease onset and extends survival in a rat model of inherited amyotrophic lateral sclerosis.

Goursaud S, Schäfer S, Dumont AO, Vergouts M, Gallo A, Desmet N, Deumens R, Hermans E. Goursaud S, et al. Among authors: desmet n. Exp Neurol. 2015 Jan;263:91-101. doi: 10.1016/j.expneurol.2014.09.022. Epub 2014 Oct 13. Exp Neurol. 2015. PMID: 25311268

4

Inhibition of the regulator of G protein signalling RGS4 in the spinal cord decreases neuropathic hyperalgesia and restores cannabinoid CB1 receptor signalling.

Bosier B, Doyen PJ, Brolet A, Muccioli GG, Ahmed E, Desmet N, Hermans E, Deumens R. Bosier B, et al. Among authors: desmet n. Br J Pharmacol. 2015 Nov;172(22):5333-46. doi: 10.1111/bph.13324. Epub 2015 Oct 25. Br J Pharmacol. 2015. PMID: 26478461 Free PMC article.

5

Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain.

Doyen PJ, Vergouts M, Pochet A, Desmet N, van Neerven S, Brook G, Hermans E. Doyen PJ, et al. Among authors: desmet n. J Neuroinflammation. 2017 Oct 27;14(1):209. doi: 10.1186/s12974-017-0971-x. J Neuroinflammation. 2017. PMID: 29078779 Free PMC article.

6

Pharmacological evidence for the concept of spare glutamate transporters.

Belo do Nascimento I, Damblon J, Ingelbrecht C, Goursaud S, Massart M, Dumont A, Desmet N, Hermans E. Belo do Nascimento I, et al. Among authors: desmet n. Neurochem Int. 2021 Oct;149:105142. doi: 10.1016/j.neuint.2021.105142. Epub 2021 Jul 24. Neurochem Int. 2021. PMID: 34314789

7

Validation of a System x_c ^- Functional Assay in Cultured Astrocytes and Nervous Tissue Samples.

Beckers P, Lara O, Belo do Nascimento I, Desmet N, Massie A, Hermans E. Beckers P, et al. Among authors: desmet n. Front Cell Neurosci. 2022 Jan 13;15:815771. doi: 10.3389/fncel.2021.815771. eCollection 2021. Front Cell Neurosci. 2022. PMID: 35095428 Free PMC article.

8

AMPK Modulates the Metabolic Adaptation of C6 Glioma Cells in Glucose-Deprived Conditions without Affecting Glutamate Transport.

Belo do Nascimento I, Verfaillie M, Ates G, Beckers P, Joris V, Desmet N, Massie A, Hermans E. Belo do Nascimento I, et al. Among authors: desmet n. Cells. 2022 May 31;11(11):1800. doi: 10.3390/cells11111800. Cells. 2022. PMID: 35681495 Free PMC article.

9

AMPKα1 Deficiency in Astrocytes from a Rat Model of ALS Is Associated with an Altered Metabolic Resilience.

Belo do Nascimento I, Ates G, Desmet N, Beckers P, Massie A, Hermans E. Belo do Nascimento I, et al. Among authors: desmet n. Biomolecules. 2023 Jul 28;13(8):1183. doi: 10.3390/biom13081183. Biomolecules. 2023. PMID: 37627248 Free PMC article.

10

Implication of system x_c^- in neuroinflammation during the onset and maintenance of neuropathic pain.

Beckers P, Belo Do Nascimento I, Charlier M, Desmet N, Massie A, Hermans E. Beckers P, et al. Among authors: desmet n. J Neuroinflammation. 2024 May 7;21(1):117. doi: 10.1186/s12974-024-03112-9. J Neuroinflammation. 2024. PMID: 38715127 Free PMC article.

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