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Variable or variate? A conundrum in pharmacometrics exposure-response models.
Grisic AM, Venkatakrishnan K, French J, Khandelwal A. Grisic AM, et al. Among authors: french j. CPT Pharmacometrics Syst Pharmacol. 2023 Feb;12(2):144-147. doi: 10.1002/psp4.12905. Epub 2022 Dec 29. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36537836 Free PMC article.
Pharmacometrics and Systems Pharmacology 2030.
Mentré F, Friberg LE, Duffull S, French J, Lauffenburger DA, Li L, Mager DE, Sinha V, Sobie E, Zhao P. Mentré F, et al. Among authors: french j. Clin Pharmacol Ther. 2020 Jan;107(1):76-78. doi: 10.1002/cpt.1683. Epub 2019 Nov 23. Clin Pharmacol Ther. 2020. PMID: 31758700
Welcome to the statistics and pharmacometrics themed issue.
French J, Mentré F. French J, et al. CPT Pharmacometrics Syst Pharmacol. 2021 Apr;10(4):273-274. doi: 10.1002/psp4.12625. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33951754 Free PMC article. No abstract available.
CPT: Pharmacometrics & Systems Pharmacology - Inception, Maturation, and Future Vision.
Rowland Yeo K, Hennig S, Krishnaswami S, Strydom N, Ayyar VS, French J, Sinha V, Sobie E, Zhao P, Friberg LE, Mentré F. Rowland Yeo K, et al. Among authors: french j. CPT Pharmacometrics Syst Pharmacol. 2021 Jul;10(7):649-657. doi: 10.1002/psp4.12680. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34298582 Free PMC article. No abstract available.
Exposure-response analysis of efficacy and safety for pexidartinib in patients with tenosynovial giant cell tumor.
Yin O, Zahir H, French J, Polhamus D, Wang X, van de Sande M, Tap WD, Gelderblom H, Wagner AJ, Healey JH, Greenberg J, Shuster D, Stacchiotti S. Yin O, et al. Among authors: french j. CPT Pharmacometrics Syst Pharmacol. 2021 Nov;10(11):1422-1432. doi: 10.1002/psp4.12712. Epub 2021 Oct 14. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34585528 Free PMC article.
Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab.
Terranova N, French J, Dai H, Wiens M, Khandelwal A, Ruiz-Garcia A, Manitz J, von Heydebreck A, Ruisi M, Chin K, Girard P, Venkatakrishnan K. Terranova N, et al. Among authors: french j. CPT Pharmacometrics Syst Pharmacol. 2022 Mar;11(3):333-347. doi: 10.1002/psp4.12754. Epub 2022 Jan 19. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 34971492 Free PMC article. Clinical Trial.
Pharmacometrics Golems: Exposure-Response Models in Oncology.
Khandelwal A, Grisic AM, French J, Venkatakrishnan K. Khandelwal A, et al. Among authors: french j. Clin Pharmacol Ther. 2022 Nov;112(5):941-945. doi: 10.1002/cpt.2564. Epub 2022 Mar 14. Clin Pharmacol Ther. 2022. PMID: 35286713 No abstract available.
Disease trajectory of SLE clinical endpoints and covariates affecting disease severity and probability of response: Analysis of pooled patient-level placebo (Standard-of-Care) data to enable model-informed drug development.
Goteti K, French J, Garcia R, Li Y, Casset-Semanaz F, Aydemir A, Townsend R, Mateo CV, Studham M, Guenther O, Kao A, Gastonguay M, Girard P, Benincosa L, Venkatakrishnan K. Goteti K, et al. Among authors: french j. CPT Pharmacometrics Syst Pharmacol. 2023 Feb;12(2):180-195. doi: 10.1002/psp4.12888. Epub 2022 Nov 29. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36350330 Free PMC article.
Confounded exposure metrics.
Wiens MR, French JL, Rogers JA. Wiens MR, et al. CPT Pharmacometrics Syst Pharmacol. 2024 Feb;13(2):187-191. doi: 10.1002/psp4.13074. Epub 2023 Nov 20. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 37984457 Free PMC article. No abstract available.
Bayesian estimation in NONMEM.
Johnston CK, Waterhouse T, Wiens M, Mondick J, French J, Gillespie WR. Johnston CK, et al. Among authors: french j. CPT Pharmacometrics Syst Pharmacol. 2024 Feb;13(2):192-207. doi: 10.1002/psp4.13088. Epub 2023 Dec 8. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38017712 Free PMC article.
2,444 results