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3,5,7-Substituted Pyrazolo[4,3- d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models.
Jorda R, Havlíček L, Šturc A, Tušková D, Daumová L, Alam M, Škerlová J, Nekardová M, Peřina M, Pospíšil T, Široká J, Urbánek L, Pachl P, Řezáčová P, Strnad M, Klener P, Kryštof V. Jorda R, et al. Among authors: perina m. J Med Chem. 2019 May 9;62(9):4606-4623. doi: 10.1021/acs.jmedchem.9b00189. Epub 2019 Apr 17. J Med Chem. 2019. PMID: 30943029
Synthesis of dihydrotestosterone derivatives modified in the A-ring with (hetero)arylidene, pyrazolo[1,5-a]pyrimidine and triazolo[1,5-a]pyrimidine moieties and their targeting of the androgen receptor in prostate cancer.
Kiss MA, Peřina M, Bazgier V, May NV, Baji Á, Jorda R, Frank É. Kiss MA, et al. Among authors: perina m. J Steroid Biochem Mol Biol. 2021 Jul;211:105904. doi: 10.1016/j.jsbmb.2021.105904. Epub 2021 Apr 29. J Steroid Biochem Mol Biol. 2021. PMID: 33933576 Free article.
3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.
Dayal N, Řezníčková E, Hernandez DE, Peřina M, Torregrosa-Allen S, Elzey BD, Škerlová J, Ajani H, Djukic S, Vojáčková V, Lepšík M, Řezáčová P, Kryštof V, Jorda R, Sintim HO. Dayal N, et al. Among authors: perina m. J Med Chem. 2021 Aug 12;64(15):10981-10996. doi: 10.1021/acs.jmedchem.1c00330. Epub 2021 Jul 21. J Med Chem. 2021. PMID: 34288692
35 results