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Impact of Cytochrome Induction or Inhibition on the Plasma and Brain Kinetics of [11C]metoclopramide, a PET Probe for P-Glycoprotein Function at the Blood-Brain Barrier.
Breuil L, Ziani N, Leterrier S, Hugon G, Caillé F, Bouilleret V, Truillet C, Goislard M, El Biali M, Bauer M, Langer O, Goutal S, Tournier N. Breuil L, et al. Pharmaceutics. 2022 Nov 30;14(12):2650. doi: 10.3390/pharmaceutics14122650. Pharmaceutics. 2022. PMID: 36559144 Free PMC article.
Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib.
Tournier N, Goutal S, Mairinger S, Hernández-Lozano I, Filip T, Sauberer M, Caillé F, Breuil L, Stanek J, Freeman AF, Novarino G, Truillet C, Wanek T, Langer O. Tournier N, et al. Among authors: breuil l. J Cereb Blood Flow Metab. 2021 Jul;41(7):1634-1646. doi: 10.1177/0271678X20965500. Epub 2020 Oct 20. J Cereb Blood Flow Metab. 2021. PMID: 33081568 Free PMC article.
23 results