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ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylation.
Wang L, Shi R, Wang S, Duan Y, Wang Z, Zheng P, Sun X, Chen X, Ji G, Shen Y, Dong B, Lin Y, Wen T, Tian Q, Guo Z, Hou Y, Wu S, Xiao L, Li M, Xiao L, Wu Q, Meng Y, Liu G, Duan S, Bai X, Liu T, Zhang Z, Zhan P, Lu Z, Xu D. Wang L, et al. Among authors: liu g. Nat Chem Biol. 2025 Jan 29. doi: 10.1038/s41589-024-01825-9. Online ahead of print. Nat Chem Biol. 2025. PMID: 39881212
Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation.
Jing Y, Jiang X, Ji Q, Wu Z, Wang W, Liu Z, Guillen-Garcia P, Esteban CR, Reddy P, Horvath S, Li J, Geng L, Hu Q, Wang S, Izpisua Belmonte JC, Ren J, Zhang W, Qu J, Liu GH. Jing Y, et al. Among authors: liu gh. Cell Stem Cell. 2025 Jan 28:S1934-5909(25)00007-4. doi: 10.1016/j.stem.2025.01.007. Online ahead of print. Cell Stem Cell. 2025. PMID: 39879990 No abstract available.
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