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Surface-modified measles vaccines encoding oligomeric, fusion-stabilized SARS-CoV-2 spike glycoproteins bypass measles seropositivity, boosting neutralizing antibody responses to omicron and historical variants.
Muñoz-Alía MÁ, Nace RA, Balakrishnan B, Zhang L, Packiriswamy N, Singh G, Warang P, Mena I, Narjari R, Vandergaast R, García-Sastre A, Schotsaert M, Russell SJ. Muñoz-Alía MÁ, et al. bioRxiv [Preprint]. 2022 Dec 16:2022.12.16.520799. doi: 10.1101/2022.12.16.520799. bioRxiv. 2022. Update in: mBio. 2024 Feb 14;15(2):e0292823. doi: 10.1128/mbio.02928-23 PMID: 36561187 Free PMC article. Updated. Preprint.
Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2.
Tummino TA, Rezelj VV, Fischer B, Fischer A, O'Meara MJ, Monel B, Vallet T, Zhang Z, Alon A, O'Donnell HR, Lyu J, Schadt H, White KM, Krogan NJ, Urban L, Shokat KM, Kruse AC, García-Sastre A, Schwartz O, Moretti F, Vignuzzi M, Pognan F, Shoichet BK. Tummino TA, et al. bioRxiv [Preprint]. 2021 Mar 24:2021.03.23.436648. doi: 10.1101/2021.03.23.436648. bioRxiv. 2021. PMID: 33791693 Free PMC article. Preprint.
Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine.
Rathnasinghe R, Salvatore M, Zheng H, Jangra S, Kehrer T, Mena I, Schotsaert M, Muster T, Palese P, García-Sastre A. Rathnasinghe R, et al. bioRxiv [Preprint]. 2021 Apr 28:2021.04.28.441797. doi: 10.1101/2021.04.28.441797. bioRxiv. 2021. Update in: Sci Rep. 2021 Nov 12;11(1):22164. doi: 10.1038/s41598-021-01780-8 PMID: 33948589 Free PMC article. Updated. Preprint.
Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant.
Thorne LG, Bouhaddou M, Reuschl AK, Zuliani-Alvarez L, Polacco B, Pelin A, Batra J, Whelan MVX, Ummadi M, Rojc A, Turner J, Obernier K, Braberg H, Soucheray M, Richards A, Chen KH, Harjai B, Memon D, Hosmillo M, Hiatt J, Jahun A, Goodfellow IG, Fabius JM, Shokat K, Jura N, Verba K, Noursadeghi M, Beltrao P, Swaney DL, Garcia-Sastre A, Jolly C, Towers GJ, Krogan NJ. Thorne LG, et al. bioRxiv [Preprint]. 2021 Jun 7:2021.06.06.446826. doi: 10.1101/2021.06.06.446826. bioRxiv. 2021. Update in: Nature. 2022 Feb;602(7897):487-495. doi: 10.1038/s41586-021-04352-y PMID: 34127972 Free PMC article. Updated. Preprint.
Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer.
Cool K, Gaudreault NN, Morozov I, Trujillo JD, Meekins DA, McDowell C, Carossino M, Bold D, Kwon T, Balaraman V, Madden DW, Artiaga BL, Pogranichniy RM, Sosa GR, Henningson J, Wilson WC, Balasuriya UBR, García-Sastre A, Richt JA. Cool K, et al. bioRxiv [Preprint]. 2021 Aug 24:2021.08.15.456341. doi: 10.1101/2021.08.15.456341. bioRxiv. 2021. Update in: Emerg Microbes Infect. 2022 Dec;11(1):95-112. doi: 10.1080/22221751.2021.2012528 PMID: 34426811 Free PMC article. Updated. Preprint.
Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant.
Gaudreault NN, Cool K, Trujillo JD, Morozov I, Meekins DA, McDowell C, Bold D, Carossino M, Balaraman V, Mitzel D, Kwon T, Madden DW, Artiaga BL, Pogranichniy RM, Roman-Sosa G, Wilson WC, Balasuriya UBR, García-Sastre A, Richt JA. Gaudreault NN, et al. bioRxiv [Preprint]. 2021 Nov 22:2021.11.15.468720. doi: 10.1101/2021.11.15.468720. bioRxiv. 2021. Update in: Emerg Microbes Infect. 2022 Dec;11(1):662-675. doi: 10.1080/22221751.2022.2037397 PMID: 34816258 Free PMC article. Updated. Preprint.
Unambiguous detection of SARS-CoV-2 subgenomic mRNAs with single cell RNA sequencing.
Cohen P, DeGrace EJ, Danziger O, Patel RS, Barrall EA, Bobrowski T, Kehrer T, Cupic A, Miorin L, García-Sastre A, Rosenberg BR. Cohen P, et al. bioRxiv [Preprint]. 2023 Feb 23:2021.11.22.469642. doi: 10.1101/2021.11.22.469642. bioRxiv. 2023. Update in: Microbiol Spectr. 2023 Sep 7:e0077623. doi: 10.1128/spectrum.00776-23 PMID: 34845443 Free PMC article. Updated. Preprint.
The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters.
Miorin L, Mire CE, Ranjbar S, Hume AJ, Huang J, Crossland NA, White KM, Laporte M, Kehrer T, Haridas V, Moreno E, Nambu A, Jangra S, Cupic A, Dejosez M, Abo KA, Tseng AE, Werder RB, Rathnasinghe R, Mutetwa T, Ramos I, de Aja JS, de Alba Rivas CG, Schotsaert M, Corley RB, Falvo JV, Fernandez-Sesma A, Kim C, Rossignol JF, Wilson AA, Zwaka T, Kotton DN, Mühlberger E, García-Sastre A, Goldfeld AE. Miorin L, et al. bioRxiv [Preprint]. 2022 Feb 9:2022.02.08.479634. doi: 10.1101/2022.02.08.479634. bioRxiv. 2022. PMID: 35169796 Free PMC article. Preprint.
Trivalent NDV-HXP-S vaccine protects against phylogenetically distant SARS-CoV-2 variants of concern in mice.
González-Domínguez I, Martínez JL, Slamanig S, Lemus N, Liu Y, Lai TY, Carreño JM, Singh A G, Singh B G, Schotsaert M, Mena I, McCroskery S, Coughlan L, Krammer F, García-Sastre A, Palese P, Sun W. González-Domínguez I, et al. bioRxiv [Preprint]. 2022 Mar 22:2022.03.21.485247. doi: 10.1101/2022.03.21.485247. bioRxiv. 2022. Update in: Microbiol Spectr. 2022 Jun 29;10(3):e0153822. doi: 10.1128/spectrum.01538-22 PMID: 35350201 Free PMC article. Updated. Preprint.
Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia.
Castaneda DC, Jangra S, Yurieva M, Martinek J, Callender M, Coxe M, Choi A, Diego JG, Lin J, Wu TC, Marches F, Chaussabel D, Yu P, Salner A, Aucello G, Koff J, Hudson B, Church SE, Gorman K, Anguiano E, García-Sastre A, Williams A, Schotsaert M, Palucka K. Castaneda DC, et al. bioRxiv [Preprint]. 2023 Mar 31:2023.03.30.534980. doi: 10.1101/2023.03.30.534980. bioRxiv. 2023. Update in: iScience. 2023 Jul 13;26(8):107374. doi: 10.1016/j.isci.2023.107374 PMID: 37034597 Free PMC article. Updated. Preprint.
828 results