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474 results

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Page 1
Continuous germinal center invasion contributes to the diversity of the immune response.
Hägglöf T, Cipolla M, Loewe M, Chen ST, Mesin L, Hartweger H, ElTanbouly MA, Cho A, Gazumyan A, Ramos V, Stamatatos L, Oliveira TY, Nussenzweig MC, Viant C. Hägglöf T, et al. Among authors: nussenzweig mc. Cell. 2023 Jan 5;186(1):147-161.e15. doi: 10.1016/j.cell.2022.11.032. Epub 2022 Dec 23. Cell. 2023. PMID: 36565698 Free PMC article.
Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies.
Greaney AJ, Starr TN, Barnes CO, Weisblum Y, Schmidt F, Caskey M, Gaebler C, Cho A, Agudelo M, Finkin S, Wang Z, Poston D, Muecksch F, Hatziioannou T, Bieniasz PD, Robbiani DF, Nussenzweig MC, Bjorkman PJ, Bloom JD. Greaney AJ, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2021 Mar 18:2021.03.17.435863. doi: 10.1101/2021.03.17.435863. bioRxiv. 2021. Update in: Nat Commun. 2021 Jul 7;12(1):4196. doi: 10.1038/s41467-021-24435-8 PMID: 33758856 Free PMC article. Updated. Preprint.
Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies.
Muecksch F, Weisblum Y, Barnes CO, Schmidt F, Schaefer-Babajew D, Lorenzi JCC, Flyak AI, DeLaitsch AT, Huey-Tubman KE, Hou S, Schiffer CA, Gaebler C, Wang Z, Da Silva J, Poston D, Finkin S, Cho A, Cipolla M, Oliveira TY, Millard KG, Ramos V, Gazumyan A, Rutkowska M, Caskey M, Nussenzweig MC, Bjorkman PJ, Hatziioannou T, Bieniasz PD. Muecksch F, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2021 Mar 8:2021.03.07.434227. doi: 10.1101/2021.03.07.434227. bioRxiv. 2021. Update in: Immunity. 2021 Aug 10;54(8):1853-1868.e7. doi: 10.1016/j.immuni.2021.07.008 PMID: 33758864 Free PMC article. Updated. Preprint.
Naturally enhanced neutralizing breadth to SARS-CoV-2 after one year.
Wang Z, Muecksch F, Schaefer-Babajew D, Finkin S, Viant C, Gaebler C, Hoffmann HH, Barnes CO, Cipolla M, Ramos V, Oliveira TY, Cho A, Schmidt F, da Silva J, Bednarski E, Aguado L, Yee J, Daga M, Turroja M, Millard KG, Jankovic M, Gazumyan A, Zhao Z, Rice CM, Bieniasz PD, Caskey M, Hatziioannou T, Nussenzweig MC. Wang Z, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2021 Jun 2:2021.05.07.443175. doi: 10.1101/2021.05.07.443175. bioRxiv. 2021. Update in: Nature. 2021 Jul;595(7867):426-431. doi: 10.1038/s41586-021-03696-9 PMID: 34100013 Free PMC article. Updated. Preprint.
Plasma neutralization properties of the SARS-CoV-2 Omicron variant.
Schmidt F, Muecksch F, Weisblum Y, Da Silva J, Bednarski E, Cho A, Wang Z, Gaebler C, Caskey M, Nussenzweig MC, Hatziioannou T, Bieniasz PD. Schmidt F, et al. Among authors: nussenzweig mc. medRxiv [Preprint]. 2021 Dec 13:2021.12.12.21267646. doi: 10.1101/2021.12.12.21267646. medRxiv. 2021. Update in: N Engl J Med. 2022 Feb 10;386(6):599-601. doi: 10.1056/NEJMc2119641 PMID: 34931199 Free PMC article. Updated. Preprint.
Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins.
Wang Z, Muecksch F, Cho A, Gaebler C, Hoffmann HH, Ramos V, Zong S, Cipolla M, Johnson B, Schmidt F, DaSilva J, Bednarski E, Tanfous TB, Raspe R, Yao K, Lee YE, Chen T, Turroja M, Milard KG, Dizon J, Kaczynska A, Gazumyan A, Oliveira TY, Rice CM, Caskey M, Bieniasz PD, Hatziioannou T, Barnes CO, Nussenzweig MC. Wang Z, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2022 Feb 1:2022.02.01.478695. doi: 10.1101/2022.02.01.478695. bioRxiv. 2022. Update in: Immunity. 2022 Jun 14;55(6):998-1012.e8. doi: 10.1016/j.immuni.2022.04.003 PMID: 35132412 Free PMC article. Updated. Preprint.
Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape.
Witte L, Baharani V, Schmidt F, Wang Z, Cho A, Raspe R, Guzman-Cardozo MC, Muecksch F, Gaebler C, Caskey M, Nussenzweig MC, Hatziioannou T, Bieniasz PD. Witte L, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2022 Aug 19:2022.08.17.504313. doi: 10.1101/2022.08.17.504313. bioRxiv. 2022. Update in: Nat Commun. 2023 Jan 19;14(1):302. doi: 10.1038/s41467-023-35927-0 PMID: 36032981 Free PMC article. Updated. Preprint.
Gene Editing of Primary Rhesus Macaque B Cells.
Hartweger H, Gautam R, Nishimura Y, Schmidt F, Yao KH, Escolano A, Jankovic M, Martin MA, Nussenzweig MC. Hartweger H, et al. Among authors: nussenzweig mc. J Vis Exp. 2023 Feb 10;(192):10.3791/64858. doi: 10.3791/64858. J Vis Exp. 2023. PMID: 36847375 Free PMC article.
SARS-CoV-2 spike glycosylation affects function and neutralization sensitivity.
Zhang F, Schmidt F, Muecksch F, Wang Z, Gazumyan A, Nussenzweig MC, Gaebler C, Caskey M, Hatziioannou T, Bieniasz PD. Zhang F, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2023 Jun 30:2023.06.30.547241. doi: 10.1101/2023.06.30.547241. bioRxiv. 2023. Update in: mBio. 2024 Feb 14;15(2):e0167223. doi: 10.1128/mbio.01672-23 PMID: 37425700 Free PMC article. Updated. Preprint.
474 results