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Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket.
Morstein J, Bowcut V, Fernando M, Yang Y, Zhu L, Jenkins ML, Evans JT, Guiley KZ, Peacock DM, Krahnke S, Lin Z, Taran KA, Huang BJ, Stephen AG, Burke JE, Lightstone FC, Shokat KM. Morstein J, et al. Among authors: huang bj. Cell. 2024 Oct 31;187(22):6379-6392.e17. doi: 10.1016/j.cell.2024.08.017. Epub 2024 Sep 9. Cell. 2024. PMID: 39255801 Free PMC article.
CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target.
Le Q, Hadland B, Smith JL, Leonti A, Huang BJ, Ries R, Hylkema TA, Castro S, Tang TT, McKay CN, Perkins L, Pardo L, Sarthy J, Beckman AK, Williams R, Idemmili R, Furlan S, Ishida T, Call L, Srivastava S, Loeb AM, Milano F, Imren S, Morris SM, Pakiam F, Olson JM, Loken MR, Brodersen L, Riddell SR, Tarlock K, Bernstein ID, Loeb KR, Meshinchi S. Le Q, et al. Among authors: huang bj. J Clin Invest. 2024 Aug 15;134(16):e184305. doi: 10.1172/JCI184305. J Clin Invest. 2024. PMID: 39145456 Free PMC article. No abstract available.
Targeting Hyperactive Ras Signaling in Pediatric Cancer.
Levinson A, Shannon K, Huang BJ. Levinson A, et al. Among authors: huang bj. Cold Spring Harb Perspect Med. 2024 Jul 15:a041572. doi: 10.1101/cshperspect.a041572. Online ahead of print. Cold Spring Harb Perspect Med. 2024. PMID: 39009442
240 results