Zhang M - Search Results

1

Activation mechanisms of clinically distinct B-Raf V600E and V600K mutants.

Zhang M, Maloney R, Liu Y, Jang H, Nussinov R. Zhang M, et al. Cancer Commun (Lond). 2023 Mar;43(3):405-408. doi: 10.1002/cac2.12395. Epub 2022 Dec 26. Cancer Commun (Lond). 2023. PMID: 36573259 Free PMC article. No abstract available.

2

Strategy toward Kinase-Selective Drug Discovery.

Zhang M, Liu Y, Jang H, Nussinov R. Zhang M, et al. J Chem Theory Comput. 2023 Mar 14;19(5):1615-1628. doi: 10.1021/acs.jctc.2c01171. Epub 2023 Feb 23. J Chem Theory Comput. 2023. PMID: 36815703 Free PMC article.

3

AlphaFold, allosteric, and orthosteric drug discovery: Ways forward.

Nussinov R, Zhang M, Liu Y, Jang H. Nussinov R, et al. Among authors: zhang m. Drug Discov Today. 2023 Jun;28(6):103551. doi: 10.1016/j.drudis.2023.103551. Epub 2023 Mar 11. Drug Discov Today. 2023. PMID: 36907321 Free PMC article. Review.

4

Neurodevelopmental disorders, like cancer, are connected to impaired chromatin remodelers, PI3K/mTOR, and PAK1-regulated MAPK.

Nussinov R, Yavuz BR, Arici MK, Demirel HC, Zhang M, Liu Y, Tsai CJ, Jang H, Tuncbag N. Nussinov R, et al. Among authors: zhang m. Biophys Rev. 2023 Apr 1;15(2):163-181. doi: 10.1007/s12551-023-01054-9. eCollection 2023 Apr. Biophys Rev. 2023. PMID: 37124926 Free PMC article. Review.

5

Spatial Mechano-Signaling Regulation of GTPases through Non-Degradative Ubiquitination.

Sewduth RN, Carai P, Ivanisevic T, Zhang M, Jang H, Lechat B, Van Haver D, Impens F, Nussinov R, Jones E, Sablina A. Sewduth RN, et al. Among authors: zhang m. Adv Sci (Weinh). 2023 Dec;10(36):e2303367. doi: 10.1002/advs.202303367. Epub 2023 Nov 9. Adv Sci (Weinh). 2023. PMID: 37946677 Free PMC article.

6

K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins.

Magits W, Steklov M, Jang H, Sewduth RN, Florentin A, Lechat B, Sheryazdanova A, Zhang M, Simicek M, Prag G, Nussinov R, Sablina A. Magits W, et al. Among authors: zhang m. EMBO J. 2024 Jul;43(14):2862-2877. doi: 10.1038/s44318-024-00146-w. Epub 2024 Jun 10. EMBO J. 2024. PMID: 38858602 Free PMC article.

7

Effects of physical multimorbidity on cognitive decline trajectories among adults aged 50 years and older with different wealth status: a 17-year population-based cohort study.

Chen C, Zhang S, Huang N, Zhang M, Fu J, Guo J. Chen C, et al. Among authors: zhang m. Glob Ment Health (Camb). 2025 Jan 3;11:e131. doi: 10.1017/gmh.2024.141. eCollection 2024. Glob Ment Health (Camb). 2025. PMID: 39777001 Free PMC article.

8

Single-cell Atlas reveals core function of CPVL/MSR1 expressing macrophages in the prognosis of triple-negative breast cancer.

Wang X, Lin L, Zhang X, Zhang M, Sun Z, Yang Y, Zhang X, Yuan Y, Zhang Y, Chen H, Wen T. Wang X, et al. Among authors: zhang m. Front Immunol. 2024 Dec 24;15:1501009. doi: 10.3389/fimmu.2024.1501009. eCollection 2024. Front Immunol. 2024. PMID: 39776914 Free PMC article.

9

The systemic inflammation response index (SIRI) predicts survival in advanced non-small cell lung cancer patients undergoing immunotherapy and the construction of a nomogram model.

Tang C, Zhang M, Jia H, Wang T, Wu H, Xu K, Ren T, Liang L. Tang C, et al. Among authors: zhang m. Front Immunol. 2024 Dec 24;15:1516737. doi: 10.3389/fimmu.2024.1516737. eCollection 2024. Front Immunol. 2024. PMID: 39776905 Free PMC article.

10

Ultra-small quercetin-based nanotherapeutics ameliorate acute liver failure by combatting inflammation/cellular senescence cycle.

Feng Y, Zhang X, Li J, Fu S, Xu W, Liu J, Yang Y, Chen T, Zhao Y, Li D, Zhang M, He Y. Feng Y, et al. Among authors: zhang m. Theranostics. 2025 Jan 1;15(3):1035-1056. doi: 10.7150/thno.103746. eCollection 2025. Theranostics. 2025. PMID: 39776808 Free PMC article.

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