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HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia.
Agrawal-Singh S, Bagri J, Giotopoulos G, Azazi DMA, Horton SJ, Lopez CK, Anand S, Bach AS, Stedham F, Antrobus R, Houghton JW, Vassiliou GS, Sasca D, Yun H, Whetton AD, Huntly BJP. Agrawal-Singh S, et al. Among authors: antrobus r. Blood. 2023 Apr 6;141(14):1737-1754. doi: 10.1182/blood.2022016528. Blood. 2023. PMID: 36577137 Free PMC article.
Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective.
Wilson EL, Yu Y, Leal NS, Woodward JA, Patikas N, Morris JL, Field SF, Plumbly W, Paupe V, Chowdhury SR, Antrobus R, Lindop GE, Adia YM, Loh SHY, Prudent J, Martins LM, Metzakopian E. Wilson EL, et al. Among authors: antrobus r. Cell Death Dis. 2024 Mar 11;15(3):203. doi: 10.1038/s41419-024-06568-y. Cell Death Dis. 2024. PMID: 38467609 Free PMC article.
Glutarate regulates T cell metabolism and anti-tumour immunity.
Minogue E, Cunha PP, Wadsworth BJ, Grice GL, Sah-Teli SK, Hughes R, Bargiela D, Quaranta A, Zurita J, Antrobus R, Velica P, Barbieri L, Wheelock CE, Koivunen P, Nathan JA, Foskolou IP, Johnson RS. Minogue E, et al. Among authors: antrobus r. Nat Metab. 2023 Oct;5(10):1747-1764. doi: 10.1038/s42255-023-00855-2. Epub 2023 Aug 21. Nat Metab. 2023. PMID: 37605057 Free PMC article.
Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity.
Potts M, Fletcher-Etherington A, Nightingale K, Mescia F, Bergamaschi L, Calero-Nieto FJ, Antrobus R, Williamson J; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Parsons H, Huttlin EL, Kingston N, Göttgens B, Bradley JR, Lehner PJ, Matheson NJ, Smith KGC, Wills MR, Lyons PA, Weekes MP. Potts M, et al. Among authors: antrobus r. Cell Rep. 2023 Jun 27;42(6):112613. doi: 10.1016/j.celrep.2023.112613. Epub 2023 May 29. Cell Rep. 2023. PMID: 37302069 Free PMC article.
Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice.
Sandovici I, Fernandez-Twinn DS, Campbell N, Cooper WN, Sekita Y, Zvetkova I, Ferland-McCollough D, Prosser HM, Oyama LM, Pantaleão LC, Cimadomo D, Barbosa de Queiroz K, Cheuk CSK, Smith NM, Kay RG, Antrobus R, Hoelle K, Ma MKL, Smith NH, Geyer SH, Reissig LF, Weninger WJ, Siddle K, Willis AE, Lam BYH, Bushell M, Ozanne SE, Constância M. Sandovici I, et al. Among authors: antrobus r. Cell Rep. 2024 Sep 24;43(9):114750. doi: 10.1016/j.celrep.2024.114750. Epub 2024 Sep 15. Cell Rep. 2024. PMID: 39283743 Free article.
Neutrophil extracellular traps protect the kidney from ascending infection and are required for a positive leukocyte dipstick test.
Stewart AP, Loudon KW, Routledge M, Lee CYC, Trotter P, Richoz N, Gillman E, Antrobus R, Mccaffrey J, Posner D, Conway Morris A, Karet Frankl FE, Clatworthy MR. Stewart AP, et al. Among authors: antrobus r. Sci Transl Med. 2024 Sep 25;16(766):eadh5090. doi: 10.1126/scitranslmed.adh5090. Epub 2024 Sep 25. Sci Transl Med. 2024. PMID: 39321268
The receptor protein tyrosine phosphatase PTPRK promotes intestinal repair and catalysis-independent tumour suppression.
Young KA, Wojdyla K, Lai T, Mulholland KE, Aldaz Casanova S, Antrobus R, Andrews SR, Biggins L, Mahler-Araujo B, Barton PR, Anderson KR, Fearnley GW, Sharpe HJ. Young KA, et al. Among authors: antrobus r. J Cell Sci. 2024 Jul 15;137(14):jcs261914. doi: 10.1242/jcs.261914. Epub 2024 Jul 22. J Cell Sci. 2024. PMID: 38904097 Free PMC article.
140 results