Smalley TB - Search Results

1

Tuaimenals B-H, Merosesquiterpenes from the Irish Deep-Sea Soft Coral Duva florida with Bioactivity against Cervical Cancer Cell Lines.

Welsch JT, Smalley TB, Matlack JK, Avalon NE, Binning JM, Johnson MP, Allcock AL, Baker BJ. Welsch JT, et al. Among authors: smalley tb. J Nat Prod. 2023 Jan 27;86(1):182-190. doi: 10.1021/acs.jnatprod.2c00898. Epub 2022 Dec 29. J Nat Prod. 2023. PMID: 36580354 Free PMC article.

2

Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral Duva florida, Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme.

Avalon NE, Nafie J, De Marco Verissimo C, Warrensford LC, Dietrick SG, Pittman AR, Young RM, Kearns FL, Smalley T, Binning JM, Dalton JP, Johnson MP, Woodcock HL, Allcock AL, Baker BJ. Avalon NE, et al. J Nat Prod. 2022 May 27;85(5):1315-1323. doi: 10.1021/acs.jnatprod.2c00054. Epub 2022 May 12. J Nat Prod. 2022. PMID: 35549259 Free PMC article. Review.

3

Structural basis for FN3K-mediated protein deglycation.

Lokhandwala J, Matlack JK, Smalley TB, Miner RE 3rd, Tran TH, Binning JM. Lokhandwala J, et al. Among authors: smalley tb. Structure. 2024 Oct 3;32(10):1711-1724.e5. doi: 10.1016/j.str.2024.07.018. Epub 2024 Aug 21. Structure. 2024. PMID: 39173621

4

The Atypical Protein Kinase C Small Molecule Inhibitor ζ-Stat, and Its Effects on Invasion Through Decreases in PKC-ζ Protein Expression.

Smalley T, Metcalf R, Patel R, Islam SMA, Bommareddy RR, Acevedo-Duncan M. Smalley T, et al. Front Oncol. 2020 Feb 27;10:209. doi: 10.3389/fonc.2020.00209. eCollection 2020. Front Oncol. 2020. PMID: 32175276 Free PMC article.

5

Simultaneous inhibition of atypical protein kinase‑C and mTOR impedes bladder cancer cell progression.

Patel R, Islam SA, Bommareddy RR, Smalley T, Acevedo-Duncan M. Patel R, et al. Int J Oncol. 2020 Jun;56(6):1373-1386. doi: 10.3892/ijo.2020.5021. Epub 2020 Mar 20. Int J Oncol. 2020. PMID: 32236625 Free PMC article.

6

Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade.

Apostolatos AH, Ratnayake WS, Win-Piazza H, Apostolatos CA, Smalley T, Kang L, Salup R, Hill R, Acevedo-Duncan M. Apostolatos AH, et al. Int J Oncol. 2018 Nov;53(5):1836-1846. doi: 10.3892/ijo.2018.4542. Epub 2018 Aug 28. Int J Oncol. 2018. PMID: 30226591 Free PMC article.

7

Analysis of PKC-ζ protein levels in normal and malignant breast tissue subtypes.

Smalley T, Islam SMA, Apostolatos C, Apostolatos A, Acevedo-Duncan M. Smalley T, et al. Oncol Lett. 2019 Feb;17(2):1537-1546. doi: 10.3892/ol.2018.9792. Epub 2018 Dec 4. Oncol Lett. 2019. PMID: 30675210 Free PMC article.

8

Effects of Atypical Protein Kinase C Inhibitor (DNDA) on Lung Cancer Proliferation and Migration by PKC-ι/FAK Ubiquitination Through the Cbl-b Pathway.

BommaReddy RR, Patel R, Smalley T, Acevedo-Duncan M. BommaReddy RR, et al. Onco Targets Ther. 2020 Feb 24;13:1661-1676. doi: 10.2147/OTT.S224866. eCollection 2020. Onco Targets Ther. 2020. PMID: 32158232 Free PMC article.

9

Structural perspectives on recent breakthrough efforts toward direct drugging of RAS and acquired resistance.

Lokhandwala J, Smalley TB, Tran TH. Lokhandwala J, et al. Among authors: smalley tb. Front Oncol. 2024 May 22;14:1394702. doi: 10.3389/fonc.2024.1394702. eCollection 2024. Front Oncol. 2024. PMID: 38841166 Free PMC article. Review.

10

Atypical Protein Kinase-C inhibitors exhibit a synergistic effect in facilitating DNA damaging effect of 5-fluorouracil in colorectal cancer cells.

Islam SMA, Dey A, Patel R, Smalley T, Acevedo-Duncan M. Islam SMA, et al. Biomed Pharmacother. 2020 Jan;121:109665. doi: 10.1016/j.biopha.2019.109665. Epub 2019 Nov 22. Biomed Pharmacother. 2020. PMID: 31810137 Free article.

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