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Dynamic 18F-Pretomanid PET imaging in animal models of TB meningitis and human studies.
Mota F, Ruiz-Bedoya CA, Tucker EW, Holt DP, De Jesus P, Lodge MA, Erice C, Chen X, Bahr M, Flavahan K, Kim J, Brosnan MK, Ordonez AA, Peloquin CA, Dannals RF, Jain SK. Mota F, et al. Among authors: holt dp. Nat Commun. 2022 Dec 29;13(1):7974. doi: 10.1038/s41467-022-35730-3. Nat Commun. 2022. PMID: 36581633 Free PMC article.
Derivatives of (-)-7-methyl-2-(5-(pyridinyl)pyridin-3-yl)-7-azabicyclo[2.2.1]heptane are potential ligands for positron emission tomography imaging of extrathalamic nicotinic acetylcholine receptors.
Gao Y, Horti AG, Kuwabara H, Ravert HT, Hilton J, Holt DP, Kumar A, Alexander M, Endres CJ, Wong DF, Dannals RF. Gao Y, et al. Among authors: holt dp. J Med Chem. 2007 Aug 9;50(16):3814-24. doi: 10.1021/jm070224t. Epub 2007 Jul 13. J Med Chem. 2007. PMID: 17629263
New synthesis and evaluation of enantiomers of 7-methyl-2-exo-(3'-iodo-5'-pyridinyl)-7-azabicyclo[2.2.1]heptane as stereoselective ligands for PET imaging of nicotinic acetylcholine receptors.
Gao Y, Horti AG, Kuwabara H, Ravert HT, Holt DP, Kumar A, Alexander M, Wong DF, Dannals RF. Gao Y, et al. Among authors: holt dp. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6168-70. doi: 10.1016/j.bmcl.2008.10.012. Epub 2008 Oct 7. Bioorg Med Chem Lett. 2008. PMID: 18930397
Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomography.
Gao Y, Ravert HT, Kuwabara H, Xiao Y, Endres CJ, Hilton J, Holt DP, Kumar A, Alexander M, Wong DF, Dannals RF, Horti AG. Gao Y, et al. Among authors: holt dp. Bioorg Med Chem. 2009 Jul 1;17(13):4367-77. doi: 10.1016/j.bmc.2009.05.021. Epub 2009 May 15. Bioorg Med Chem. 2009. PMID: 19481945 Free PMC article.
76 results