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Page 1
Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis.
Schepers M, Paes D, Tiane A, Rombaut B, Piccart E, van Veggel L, Gervois P, Wolfs E, Lambrichts I, Brullo C, Bruno O, Fedele E, Ricciarelli R, Ffrench-Constant C, Bechler ME, van Schaik P, Baron W, Lefevere E, Wasner K, Grünewald A, Verfaillie C, Baeten P, Broux B, Wieringa P, Hellings N, Prickaerts J, Vanmierlo T. Schepers M, et al. Among authors: baeten p. Brain Behav Immun. 2023 Mar;109:1-22. doi: 10.1016/j.bbi.2022.12.020. Epub 2022 Dec 28. Brain Behav Immun. 2023. PMID: 36584795 Free article.
Improving the Efficacy of Regulatory T Cell Therapy.
Baeten P, Van Zeebroeck L, Kleinewietfeld M, Hellings N, Broux B. Baeten P, et al. Clin Rev Allergy Immunol. 2022 Apr;62(2):363-381. doi: 10.1007/s12016-021-08866-1. Epub 2021 Jul 5. Clin Rev Allergy Immunol. 2022. PMID: 34224053 Free PMC article. Review.
Oncostatin M triggers brain inflammation by compromising blood-brain barrier integrity.
Hermans D, Houben E, Baeten P, Slaets H, Janssens K, Hoeks C, Hosseinkhani B, Duran G, Bormans S, Gowing E, Hoornaert C, Beckers L, Fung WK, Schroten H, Ishikawa H, Fraussen J, Thoelen R, de Vries HE, Kooij G, Zandee S, Prat A, Hellings N, Broux B. Hermans D, et al. Among authors: baeten p. Acta Neuropathol. 2022 Aug;144(2):259-281. doi: 10.1007/s00401-022-02445-0. Epub 2022 Jun 6. Acta Neuropathol. 2022. PMID: 35666306
Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.
Grajchen E, Loix M, Baeten P, Côrte-Real BF, Hamad I, Vanherle S, Haidar M, Dehairs J, Broos JY, Ntambi JM, Zimmermann R, Breinbauer R, Stinissen P, Hellings N, Verberk SGS, Kooij G, Giera M, Swinnen JV, Broux B, Kleinewietfeld M, Hendriks JJA, Bogie JFJ. Grajchen E, et al. Among authors: baeten p. Cell Mol Immunol. 2023 Jun;20(6):666-679. doi: 10.1038/s41423-023-01011-2. Epub 2023 Apr 12. Cell Mol Immunol. 2023. PMID: 37041314 Free PMC article.
Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood - brain barrier function.
Hosseinkhani B, Duran G, Hoeks C, Hermans D, Schepers M, Baeten P, Poelmans J, Coenen B, Bekar K, Pintelon I, Timmermans JP, Vanmierlo T, Michiels L, Hellings N, Broux B. Hosseinkhani B, et al. Among authors: baeten p. Fluids Barriers CNS. 2023 Dec 19;20(1):95. doi: 10.1186/s12987-023-00504-6. Fluids Barriers CNS. 2023. PMID: 38114994 Free PMC article.
Rapamycin rescues loss of function in blood-brain barrier-interacting Tregs.
Baeten P, Hamad I, Hoeks C, Hiltensperger M, Van Wijmeersch B, Popescu V, Aly L, Somers V, Korn T, Kleinewietfeld M, Hellings N, Broux B. Baeten P, et al. JCI Insight. 2024 Apr 8;9(7):e167457. doi: 10.1172/jci.insight.167457. JCI Insight. 2024. PMID: 38386413 Free PMC article.
Effect on neutrophil migration and antimicrobial functions by the Bruton's tyrosine kinase inhibitors tolebrutinib, evobrutinib and fenebrutinib.
De Bondt M, Renders J, de Prado PP, Berghmans N, Pörtner N, Vanbrabant L, de Oliveira VLS, Duran G, Baeten P, Broux B, Gouwy M, Matthys P, Hellings N, Struyf S. De Bondt M, et al. Among authors: baeten p. J Leukoc Biol. 2024 Jul 8:qiae160. doi: 10.1093/jleuko/qiae160. Online ahead of print. J Leukoc Biol. 2024. PMID: 38976501
16 results