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Page 1
Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis.
Schepers M, Paes D, Tiane A, Rombaut B, Piccart E, van Veggel L, Gervois P, Wolfs E, Lambrichts I, Brullo C, Bruno O, Fedele E, Ricciarelli R, Ffrench-Constant C, Bechler ME, van Schaik P, Baron W, Lefevere E, Wasner K, Grünewald A, Verfaillie C, Baeten P, Broux B, Wieringa P, Hellings N, Prickaerts J, Vanmierlo T. Schepers M, et al. Among authors: bruno o. Brain Behav Immun. 2023 Mar;109:1-22. doi: 10.1016/j.bbi.2022.12.020. Epub 2022 Dec 28. Brain Behav Immun. 2023. PMID: 36584795 Free article.
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology.
Paes D, Schepers M, Willems E, Rombaut B, Tiane A, Solomina Y, Tibbo A, Blair C, Kyurkchieva E, Baillie GS, Ricciarelli R, Brullo C, Fedele E, Bruno O, van den Hove D, Vanmierlo T, Prickaerts J. Paes D, et al. Among authors: bruno o. Cell Mol Life Sci. 2023 Jun 12;80(7):178. doi: 10.1007/s00018-023-04804-w. Cell Mol Life Sci. 2023. PMID: 37306762 Free PMC article.
Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition.
Schepers M, Hendrix S, Mussen F, van Breedam E, Ponsaerts P, Lemmens S, Hellings N, Ricciarelli R, Fedele E, Bruno O, Brullo C, Prickaerts J, Van Broeckhoven J, Vanmierlo T. Schepers M, et al. Among authors: bruno o. Neurotherapeutics. 2024 Jul;21(4):e00372. doi: 10.1016/j.neurot.2024.e00372. Epub 2024 May 16. Neurotherapeutics. 2024. PMID: 38760316 Free PMC article.
Rivaroxaban Prophylaxis in Noncirrhotic Portal Vein Thrombosis.
Plessier A, Goria O, Cervoni JP, Ollivier I, Bureau C, Poujol-Robert A, Minello A, Houssel-Debry P, Rautou PE, Payancé A, Scoazec G, Bruno O, Corbic M, Durand F, Vilgrain V, Paradis V, Boudaoud L, de Raucourt E, Roy C, Gault N, Valla D. Plessier A, et al. Among authors: bruno o. NEJM Evid. 2022 Dec;1(12):EVIDoa2200104. doi: 10.1056/EVIDoa2200104. Epub 2022 Nov 22. NEJM Evid. 2022. PMID: 38319842 Clinical Trial.
312 results