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Page 1
A DNA biosensors-based microfluidic platform for attomolar real-time detection of unamplified SARS-CoV-2 virus.
Robin P, Barnabei L, Marocco S, Pagnoncelli J, Nicolis D, Tarantelli C, Tavilla AC, Robortella R, Cascione L, Mayoraz L, Journot CMA, Mensi M, Bertoni F, Stefanini I, Gerber-Lemaire S. Robin P, et al. Among authors: bertoni f. Biosens Bioelectron X. 2023 May;13:100302. doi: 10.1016/j.biosx.2022.100302. Epub 2022 Dec 27. Biosens Bioelectron X. 2023. PMID: 36589921 Free PMC article.
Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor.
De Pascale M, Bissegger L, Tarantelli C, Beaufils F, Prescimone A, Mohamed Seid Hedad H, Kayali O, Orbegozo C, Raguž L, Schaefer T, Hebeisen P, Bertoni F, Wymann MP, Borsari C. De Pascale M, et al. Among authors: bertoni f. Eur J Med Chem. 2023 Feb 15;248:115038. doi: 10.1016/j.ejmech.2022.115038. Epub 2022 Dec 28. Eur J Med Chem. 2023. PMID: 36634458 Free article.
New strategies to hit hematological cancers.
Barreca M, Bertoni F, Barraja P. Barreca M, et al. Among authors: bertoni f. Eur J Med Chem. 2024 Apr 15;270:116350. doi: 10.1016/j.ejmech.2024.116350. Epub 2024 Mar 20. Eur J Med Chem. 2024. PMID: 38582688 No abstract available.
Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas.
Barreca M, Spanò V, Rocca R, Bivacqua R, Gualtieri G, Raimondi MV, Gaudio E, Bortolozzi R, Manfreda L, Bai R, Montalbano A, Alcaro S, Hamel E, Bertoni F, Viola G, Barraja P. Barreca M, et al. Among authors: bertoni f. Eur J Med Chem. 2023 Jun 5;254:115372. doi: 10.1016/j.ejmech.2023.115372. Epub 2023 Apr 12. Eur J Med Chem. 2023. PMID: 37068384 Free PMC article.
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo.
Sebastiani J, Puxeddu M, Nalli M, Bai R, Altieri L, Rovella P, Gaudio E, Trisciuoglio D, Spriano F, Lavia P, Fionda C, Masci D, Urbani A, Bigogno C, Dondio G, Hamel E, Bertoni F, Silvestri R, La Regina G. Sebastiani J, et al. Among authors: bertoni f. Eur J Med Chem. 2023 Jan 15;246:114997. doi: 10.1016/j.ejmech.2022.114997. Epub 2022 Dec 5. Eur J Med Chem. 2023. PMID: 36502578
PI3Kδ activation, IL-6 overexpression, and CD37 loss cause resistance to naratuximab emtansine in lymphomas.
Arribas AJ, Napoli S, Gaudio E, Herbaux C, Cannas E, Tarantelli C, Bordone-Pittau R, Cascione L, Munz N, Aresu L, Sgrignani J, Rinaldi A, Kwee I, Rossi D, Cavalli A, Zucca E, Stussi G, Stathis A, Sloss C, Davids MS, Bertoni F. Arribas AJ, et al. Among authors: bertoni f. Blood Adv. 2024 Dec 24;8(24):6268-6281. doi: 10.1182/bloodadvances.2023012291. Blood Adv. 2024. PMID: 39374583
Targeting CD25+ lymphoma cells with the antibody-drug conjugate camidanlumab tesirine as a single agent or in combination with targeted agents.
Spriano F, Tarantelli C, Cascione L, Gaudio E, Golino G, Scalise L, Cacciapuoti MT, Zucca E, Stathis A, Van Berkel PH, Inghirami G, Zammarchi F, Bertoni F. Spriano F, et al. Among authors: bertoni f. Br J Haematol. 2024 Nov;205(5):1873-1882. doi: 10.1111/bjh.19658. Epub 2024 Jul 30. Br J Haematol. 2024. PMID: 39080847
A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers.
Spriano F, Sartori G, Sgrignani J, Barnabei L, Arribas AJ, Guala M, Del Amor AMC, Tomasso MR, Tarantelli C, Cascione L, Golino G, Riveiro ME, Bortolozzi R, Lupia A, Paduano F, Huguet S, Rezai K, Rinaldi A, Margheriti F, Ventura P, Guarda G, Costa G, Rocca R, Furlan A, Verdonk LM, Innocenti P, Martin NI, Viola G, Driessen C, Zucca E, Stathis A, Gahtory D, Van den Nieuwboer M, Bornhauser B, Alcaro S, Trapasso F, Cristobal S, Padrick SB, Pazzi N, Cavalli F, Cavalli A, Gaudio E, Bertoni F. Spriano F, et al. Among authors: bertoni f. Haematologica. 2024 Nov 1;109(11):3602-3614. doi: 10.3324/haematol.2022.282672. Haematologica. 2024. PMID: 38899342 Free PMC article.
Selective haematological cancer eradication with preserved haematopoiesis.
Garaudé S, Marone R, Lepore R, Devaux A, Beerlage A, Seyres D, Dell' Aglio A, Juskevicius D, Zuin J, Burgold T, Wang S, Katta V, Manquen G, Li Y, Larrue C, Camus A, Durzynska I, Wellinger LC, Kirby I, Van Berkel PH, Kunz C, Tamburini J, Bertoni F, Widmer CC, Tsai SQ, Simonetta F, Urlinger S, Jeker LT. Garaudé S, et al. Among authors: bertoni f. Nature. 2024 Jun;630(8017):728-735. doi: 10.1038/s41586-024-07456-3. Epub 2024 May 22. Nature. 2024. PMID: 38778101 Free PMC article.
796 results