Oehler S - Search Results

1

Permutational Encoding Strategy Accelerates HIT Validation from Single-Stranded DNA-Encoded Libraries.

Puglioli S, Fabbri M, Comacchio C, Alvigini L, De Luca R, Oehler S, Gilardoni E, Bassi G, Cazzamalli S, Neri D, Favalli N. Puglioli S, et al. Among authors: oehler s. Bioconjug Chem. 2024 Jul 17;35(7):1033-1043. doi: 10.1021/acs.bioconjchem.4c00233. Epub 2024 Jul 4. Bioconjug Chem. 2024. PMID: 38963407

2

DNA-encoded chemical libraries enable the discovery of potent PSMA-ligands with substantially reduced affinity towards the GCPIII anti-target.

Lucaroni L, Oehler S, Georgiev T, Müller M, Bocci M, De Luca R, Favalli N, Neri D, Cazzamalli S, Prati L. Lucaroni L, et al. Among authors: oehler s. Chem Sci. 2024 Apr 2;15(18):6789-6799. doi: 10.1039/d3sc06668a. eCollection 2024 May 8. Chem Sci. 2024. PMID: 38725500 Free PMC article.

3

Discovery of Glutamate Carboxypeptidase III Ligands to Compete the Uptake of [¹⁷⁷Lu]Lu-PSMA-617 in Healthy Organs.

Müller M, Lucaroni L, Favalli N, Bassi G, Neri D, Cazzamalli S, Oehler S. Müller M, et al. Among authors: oehler s. J Med Chem. 2024 May 23;67(10):8247-8260. doi: 10.1021/acs.jmedchem.4c00332. Epub 2024 May 8. J Med Chem. 2024. PMID: 38716576

4

Impact of library input on the hit discovery rate in DNA-encoded chemical library selections.

Puglioli S, Oehler S, Prati L, Scheuermann J, Bassi G, Cazzamalli S, Neri D, Favalli N. Puglioli S, et al. Among authors: oehler s. Chem Sci. 2023 Oct 17;14(43):12026-12033. doi: 10.1039/d3sc03688j. eCollection 2023 Nov 8. Chem Sci. 2023. PMID: 37969600 Free PMC article.

5

Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries.

Torng W, Biancofiore I, Oehler S, Xu J, Xu J, Watson I, Masina B, Prati L, Favalli N, Bassi G, Neri D, Cazzamalli S, Feng JA. Torng W, et al. Among authors: oehler s. ACS Omega. 2023 Jul 6;8(28):25090-25100. doi: 10.1021/acsomega.3c01775. eCollection 2023 Jul 18. ACS Omega. 2023. PMID: 37483198 Free PMC article.

6

Site-Specific Chemical Modification of a Cytokine Mimic for Small Molecule-Based Tumor Targeting.

Mortensen M, Bertolini M, Mock J, Scheuermann J, Oehler S. Mortensen M, et al. Among authors: oehler s. Bioconjug Chem. 2023 Aug 16;34(8):1374-1379. doi: 10.1021/acs.bioconjchem.3c00194. Epub 2023 Jul 18. Bioconjug Chem. 2023. PMID: 37462264

7

A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition.

Oehler S, Lucaroni L, Migliorini F, Elsayed A, Prati L, Puglioli S, Matasci M, Schira K, Scheuermann J, Yudin D, Jia M, Ban N, Bushnell D, Kornberg R, Cazzamalli S, Neri D, Favalli N, Bassi G. Oehler S, et al. Nat Chem. 2023 Oct;15(10):1431-1443. doi: 10.1038/s41557-023-01257-3. Epub 2023 Jul 3. Nat Chem. 2023. PMID: 37400597

8

Response to: GCP III is not the "off-target" for urea-based PSMA-ligands.

Bassi G, Cazzamalli S, Oehler S, Lucaroni L, Georgiev T, Favalli N, Neri D. Bassi G, et al. Among authors: oehler s. Eur J Nucl Med Mol Imaging. 2023 Aug;50(10):2947-2949. doi: 10.1007/s00259-023-06302-4. Epub 2023 Jun 21. Eur J Nucl Med Mol Imaging. 2023. PMID: 37341746 No abstract available.

9

Cross-immunity against SARS-COV-2 variants of concern in naturally infected critically ill COVID-19 patients.

Fraser DD, Patel MA, Van Nynatten LR, Martin C, Seney SL, Miller MR, Daley M, Slessarev M, Cepinskas G, Juneja GK, Sabourin V, Fox-Robichaud A, Yeh CH, Kim PY, Badrnya S, Oehler S, Miholits M, Webb B. Fraser DD, et al. Among authors: oehler s. Heliyon. 2023 Jan;9(1):e12704. doi: 10.1016/j.heliyon.2022.e12704. Epub 2022 Dec 29. Heliyon. 2023. PMID: 36594041 Free PMC article.

10

Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics.

Lucaroni L, Georgiev T, Prodi E, Puglioli S, Pellegrino C, Favalli N, Prati L, Manz MG, Cazzamalli S, Neri D, Oehler S, Bassi G. Lucaroni L, et al. Among authors: oehler s. Eur J Nucl Med Mol Imaging. 2023 Feb;50(3):957-961. doi: 10.1007/s00259-022-05982-8. Epub 2022 Oct 3. Eur J Nucl Med Mol Imaging. 2023. PMID: 36184692

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