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Liposomal Permeation Assay for Droplet-Scale Pharmacokinetic Screening.
Hu J, Chan AI, Adaligil E, Kekessie I, Takahashi M, Song A, Cunningham CN, Paegel BM. Hu J, et al. Among authors: chan ai. J Med Chem. 2023 May 11;66(9):6288-6296. doi: 10.1021/acs.jmedchem.3c00138. Epub 2023 Apr 19. J Med Chem. 2023. PMID: 37075027 Free PMC article.
An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor.
Wang S, Woods EC, Jo J, Zhu J, Hansel-Harris A, Holcomb M, Pedowitz NJ, Upadhyay T, Bennett J, Fellner M, Park KW, Zhang A, Valdez TA, Forli S, Chan AI, Cunningham CN, Bogyo M. Wang S, et al. Among authors: chan ai. bioRxiv [Preprint]. 2024 Nov 8:2024.11.06.622387. doi: 10.1101/2024.11.06.622387. bioRxiv. 2024. PMID: 39574702 Free PMC article. Preprint.
Novel selection methods for DNA-encoded chemical libraries.
Chan AI, McGregor LM, Liu DR. Chan AI, et al. Curr Opin Chem Biol. 2015 Jun;26:55-61. doi: 10.1016/j.cbpa.2015.02.010. Epub 2015 Feb 24. Curr Opin Chem Biol. 2015. PMID: 25723146 Free PMC article. Review.
Multimodal small-molecule screening for human prion protein binders.
Reidenbach AG, Mesleh MF, Casalena D, Vallabh SM, Dahlin JL, Leed AJ, Chan AI, Usanov DL, Yehl JB, Lemke CT, Campbell AJ, Shah RN, Shrestha OK, Sacher JR, Rangel VL, Moroco JA, Sathappa M, Nonato MC, Nguyen KT, Wright SK, Liu DR, Wagner FF, Kaushik VK, Auld DS, Schreiber SL, Minikel EV. Reidenbach AG, et al. Among authors: chan ai. J Biol Chem. 2020 Sep 25;295(39):13516-13531. doi: 10.1074/jbc.RA120.014905. Epub 2020 Jul 28. J Biol Chem. 2020. PMID: 32723867 Free PMC article.
Discovery and molecular basis of subtype-selective cyclophilin inhibitors.
Peterson AA, Rangwala AM, Thakur MK, Ward PS, Hung C, Outhwaite IR, Chan AI, Usanov DL, Mootha VK, Seeliger MA, Liu DR. Peterson AA, et al. Among authors: chan ai. Nat Chem Biol. 2022 Nov;18(11):1184-1195. doi: 10.1038/s41589-022-01116-1. Epub 2022 Sep 26. Nat Chem Biol. 2022. PMID: 36163383 Free PMC article.
19 results