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Page 1
The molecular basis of tRNA selectivity by human pseudouridine synthase 3.
Lin TY, Kleemann L, Jeżowski J, Dobosz D, Rawski M, Indyka P, Ważny G, Mehta R, Chramiec-Głąbik A, Koziej Ł, Ranff T, Fufezan C, Wawro M, Kochan J, Bereta J, Leidel SA, Glatt S. Lin TY, et al. Among authors: dobosz d. Mol Cell. 2024 Jul 11;84(13):2472-2489.e8. doi: 10.1016/j.molcel.2024.06.013. Mol Cell. 2024. PMID: 38996458 Free PMC article.
Cryo-EM structures of the human Elongator complex at work.
Abbassi NE, Jaciuk M, Scherf D, Böhnert P, Rau A, Hammermeister A, Rawski M, Indyka P, Wazny G, Chramiec-Głąbik A, Dobosz D, Skupien-Rabian B, Jankowska U, Rappsilber J, Schaffrath R, Lin TY, Glatt S. Abbassi NE, et al. Among authors: dobosz d. Nat Commun. 2024 May 15;15(1):4094. doi: 10.1038/s41467-024-48251-y. Nat Commun. 2024. PMID: 38750017 Free PMC article.
Cryo-EM structure of the fully assembled Elongator complex.
Jaciuk M, Scherf D, Kaszuba K, Gaik M, Rau A, Kościelniak A, Krutyhołowa R, Rawski M, Indyka P, Graziadei A, Chramiec-Głąbik A, Biela A, Dobosz D, Lin TY, Abbassi NE, Hammermeister A, Rappsilber J, Kosinski J, Schaffrath R, Glatt S. Jaciuk M, et al. Among authors: dobosz d. Nucleic Acids Res. 2023 Mar 21;51(5):2011-2032. doi: 10.1093/nar/gkac1232. Nucleic Acids Res. 2023. PMID: 36617428 Free PMC article.
Destabilization of mutated human PUS3 protein causes intellectual disability.
Lin TY, Smigiel R, Kuzniewska B, Chmielewska JJ, Kosińska J, Biela M, Biela A, Kościelniak A, Dobosz D, Laczmanska I, Chramiec-Głąbik A, Jeżowski J, Nowak J, Gos M, Rzonca-Niewczas S, Dziembowska M, Ploski R, Glatt S. Lin TY, et al. Among authors: dobosz d. Hum Mutat. 2022 Dec;43(12):2063-2078. doi: 10.1002/humu.24471. Epub 2022 Oct 2. Hum Mutat. 2022. PMID: 36125428 Free PMC article.
Functional divergence of the two Elongator subcomplexes during neurodevelopment.
Gaik M, Kojic M, Stegeman MR, Öncü-Öner T, Kościelniak A, Jones A, Mohamed A, Chau PYS, Sharmin S, Chramiec-Głąbik A, Indyka P, Rawski M, Biela A, Dobosz D, Millar A, Chau V, Ünalp A, Piper M, Bellingham MC, Eichler EE, Nickerson DA, Güleryüz H, Abbassi NEH, Jazgar K, Davis MJ, Mercimek-Andrews S, Cingöz S, Wainwright BJ, Glatt S. Gaik M, et al. Among authors: dobosz d. EMBO Mol Med. 2022 Jul 7;14(7):e15608. doi: 10.15252/emmm.202115608. Epub 2022 Jun 13. EMBO Mol Med. 2022. PMID: 35698786 Free PMC article.