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Preclinical workup using long-read amplicon sequencing provides families with de novo pathogenic variants access to universal preimplantation genetic testing.
Tsuiko O, El Ayeb Y, Jatsenko T, Allemeersch J, Melotte C, Ding J, Debrock S, Peeraer K, Vanhie A, De Leener A, Pirard C, Kluyskens C, Denayer E, Legius E, Vermeesch JR, Brems H, Dimitriadou E. Tsuiko O, et al. Among authors: ding j. Hum Reprod. 2023 Mar 1;38(3):511-519. doi: 10.1093/humrep/deac273. Hum Reprod. 2023. PMID: 36625546
Haplotyping-based preimplantation genetic testing reveals parent-of-origin specific mechanisms of aneuploidy formation.
Tšuiko O, Vanneste M, Melotte C, Ding J, Debrock S, Masset H, Peters M, Salumets A, De Leener A, Pirard C, Kluyskens C, Hostens K, van de Vijver A, Peeraer K, Denayer E, Vermeesch JR, Dimitriadou E. Tšuiko O, et al. Among authors: ding j. NPJ Genom Med. 2021 Oct 7;6(1):81. doi: 10.1038/s41525-021-00246-0. NPJ Genom Med. 2021. PMID: 34620870 Free PMC article.
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