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TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes.
Eckfeld C, Schoeps B, Häußler D, Frädrich J, Bayerl F, Böttcher JP, Knolle P, Heisz S, Prokopchuk O, Hauner H, Munkhbaatar E, Demir IE, Hermann CD, Krüger A. Eckfeld C, et al. Among authors: prokopchuk o. J Cell Biol. 2023 Feb 6;222(2):e202206095. doi: 10.1083/jcb.202206095. Epub 2023 Jan 11. J Cell Biol. 2023. PMID: 36629908 Free PMC article.
Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver.
Grünwald B, Harant V, Schaten S, Frühschütz M, Spallek R, Höchst B, Stutzer K, Berchtold S, Erkan M, Prokopchuk O, Martignoni M, Esposito I, Heikenwalder M, Gupta A, Siveke J, Saftig P, Knolle P, Wohlleber D, Krüger A. Grünwald B, et al. Among authors: prokopchuk o. Gastroenterology. 2016 Nov;151(5):1011-1024.e7. doi: 10.1053/j.gastro.2016.07.043. Epub 2016 Aug 6. Gastroenterology. 2016. PMID: 27506299
Elevated systemic levels of the matrix metalloproteinase inhibitor TIMP-1 correlate with clinical markers of cachexia in patients with chronic pancreatitis and pancreatic cancer.
Prokopchuk O, Grünwald B, Nitsche U, Jäger C, Prokopchuk OL, Schubert EC, Friess H, Martignoni ME, Krüger A. Prokopchuk O, et al. Among authors: prokopchuk ol. BMC Cancer. 2018 Feb 2;18(1):128. doi: 10.1186/s12885-018-4055-9. BMC Cancer. 2018. PMID: 29394913 Free PMC article.
TIMP1 Triggers Neutrophil Extracellular Trap Formation in Pancreatic Cancer.
Schoeps B, Eckfeld C, Prokopchuk O, Böttcher J, Häußler D, Steiger K, Demir IE, Knolle P, Soehnlein O, Jenne DE, Hermann CD, Krüger A. Schoeps B, et al. Among authors: prokopchuk o. Cancer Res. 2021 Jul 1;81(13):3568-3579. doi: 10.1158/0008-5472.CAN-20-4125. Epub 2021 May 3. Cancer Res. 2021. PMID: 33941611
33 results