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Page 1
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis.
Xiao X, Kennelly JP, Ferrari A, Clifford BL, Whang E, Gao Y, Qian K, Sandhu J, Jarrett KE, Brearley-Sholto MC, Nguyen A, Nagari RT, Lee MS, Zhang S, Weston TA, Young SG, Bensinger SJ, Villanueva CJ, de Aguiar Vallim TQ, Tontonoz P. Xiao X, et al. Among authors: young sg. Nat Metab. 2023 Jan;5(1):165-181. doi: 10.1038/s42255-022-00722-6. Epub 2023 Jan 16. Nat Metab. 2023. PMID: 36646756 Free PMC article.
CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization.
Qian K, Tol MJ, Wu J, Uchiyama LF, Xiao X, Cui L, Bedard AH, Weston TA, Rajendran PS, Vergnes L, Shimanaka Y, Yin Y, Jami-Alahmadi Y, Cohn W, Bajar BT, Lin CH, Jin B, DeNardo LA, Black DL, Whitelegge JP, Wohlschlegel JA, Reue K, Shivkumar K, Chen FJ, Young SG, Li P, Tontonoz P. Qian K, et al. Among authors: young sg. Nature. 2023 Jan;613(7942):160-168. doi: 10.1038/s41586-022-05507-1. Epub 2022 Dec 7. Nature. 2023. PMID: 36477540 Free PMC article.
Aster-dependent non-vesicular transport facilitates dietary cholesterol uptake.
Ferrari A, Whang E, Xiao X, Kennelly JP, Romartinez-Alonso B, Mack JJ, Weston T, Chen K, Kim Y, Tol MJ, Bideyan L, Nguyen A, Gao Y, Cui L, Bedard AH, Sandhu J, Lee SD, Fairall L, Williams KJ, Song W, Munguia P, Russell RA, Martin MG, Jung ME, Jiang H, Schwabe JWR, Young SG, Tontonoz P. Ferrari A, et al. Among authors: young sg. bioRxiv [Preprint]. 2023 Jul 10:2023.07.07.548168. doi: 10.1101/2023.07.07.548168. bioRxiv. 2023. Update in: Science. 2023 Nov 10;382(6671):eadf0966. doi: 10.1126/science.adf0966 PMID: 37503112 Free PMC article. Updated. Preprint.
Hypertriglyceridemia in Apoa5-/- mice results from reduced amounts of lipoprotein lipase in the capillary lumen.
Yang Y, Beigneux AP, Song W, Nguyen LP, Jung H, Tu Y, Weston TA, Tran CM, Xie K, Yu RG, Tran AP, Miyashita K, Nakajima K, Murakami M, Chen YQ, Zhen EY, Kim JR, Kim PH, Birrane G, Tontonoz P, Ploug M, Konrad RJ, Fong LG, Young SG. Yang Y, et al. Among authors: young sg. J Clin Invest. 2023 Dec 1;133(23):e172600. doi: 10.1172/JCI172600. J Clin Invest. 2023. PMID: 37824203 Free PMC article.
Dietary control of peripheral adipose storage capacity through membrane lipid remodelling.
Tol MJ, Shimanaka Y, Bedard AH, Sapia J, Cui L, Colaço-Gaspar M, Hofer P, Ferrari A, Qian K, Kennelly JP, Lee SD, Gao Y, Xiao X, Gao J, Mack JJ, Weston TA, Pan C, Lusis AJ, Williams KJ, Su B, Pike DP, Reed A, Milosevich N, Cravatt BF, Arita M, Young SG, Ford DA, Zechner R, Vanni S, Tontonoz P. Tol MJ, et al. Among authors: young sg. bioRxiv [Preprint]. 2024 Oct 29:2024.10.25.620374. doi: 10.1101/2024.10.25.620374. bioRxiv. 2024. PMID: 39554041 Free PMC article. Preprint.
The zinc finger and BTB domain containing protein ZBTB20 regulates plasma triglyceride metabolism by repressing lipoprotein lipase gene transcription in hepatocytes.
Li H, Liu G, Wan X, Zhou L, Qin ZB, Ma XH, Su K, Liu YJ, Yuan J, Wei CC, Ren AJ, Chen YX, Young SG, Zhang H, Xie Z, Zhang WJ. Li H, et al. Among authors: young sg. Hepatology. 2022 May;75(5):1169-1180. doi: 10.1002/hep.32176. Epub 2021 Dec 1. Hepatology. 2022. PMID: 34580885 Free PMC article.
Distinct strategies for intravascular triglyceride metabolism in hearts of mammals and lower vertebrate species.
Nguyen LP, Song W, Yang Y, Tran AP, Weston TA, Jung H, Tu Y, Kim PH, Kim JR, Xie K, Yu RG, Scheithauer J, Presnell AM, Ploug M, Birrane G, Arnold H, Koltowska K, Mäe MA, Betsholtz C, He L, Goodwin JL, Beigneux AP, Fong LG, Young SG. Nguyen LP, et al. Among authors: young sg. JCI Insight. 2024 Sep 17;9(20):e184940. doi: 10.1172/jci.insight.184940. JCI Insight. 2024. PMID: 39435661 Free PMC article.
457 results