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Page 1
A structural basis for prion strain diversity.
Manka SW, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF. Manka SW, et al. Among authors: wenborn a. Nat Chem Biol. 2023 May;19(5):607-613. doi: 10.1038/s41589-022-01229-7. Epub 2023 Jan 16. Nat Chem Biol. 2023. PMID: 36646960 Free PMC article.
Prion strains viewed through the lens of cryo-EM.
Manka SW, Wenborn A, Collinge J, Wadsworth JDF. Manka SW, et al. Among authors: wenborn a. Cell Tissue Res. 2023 Apr;392(1):167-178. doi: 10.1007/s00441-022-03676-z. Epub 2022 Aug 27. Cell Tissue Res. 2023. PMID: 36028585 Free PMC article. Review.
2.7 Å cryo-EM structure of ex vivo RML prion fibrils.
Manka SW, Zhang W, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF. Manka SW, et al. Among authors: wenborn a. Nat Commun. 2022 Jul 13;13(1):4004. doi: 10.1038/s41467-022-30457-7. Nat Commun. 2022. PMID: 35831275 Free PMC article.
Highly infectious prions are not directly neurotoxic.
Benilova I, Reilly M, Terry C, Wenborn A, Schmidt C, Marinho AT, Risse E, Al-Doujaily H, Wiggins De Oliveira M, Sandberg MK, Wadsworth JDF, Jat PS, Collinge J. Benilova I, et al. Among authors: wenborn a. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23815-23822. doi: 10.1073/pnas.2007406117. Epub 2020 Sep 8. Proc Natl Acad Sci U S A. 2020. PMID: 32900920 Free PMC article.
Sod1 deficiency reduces incubation time in mouse models of prion disease.
Akhtar S, Grizenkova J, Wenborn A, Hummerich H, Fernandez de Marco M, Brandner S, Collinge J, Lloyd SE. Akhtar S, et al. Among authors: wenborn a. PLoS One. 2013;8(1):e54454. doi: 10.1371/journal.pone.0054454. Epub 2013 Jan 22. PLoS One. 2013. PMID: 23349894 Free PMC article.
Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice.
Grizenkova J, Akhtar S, Hummerich H, Tomlinson A, Asante EA, Wenborn A, Fizet J, Poulter M, Wiseman FK, Fisher EM, Tybulewicz VL, Brandner S, Collinge J, Lloyd SE. Grizenkova J, et al. Among authors: wenborn a. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13722-7. doi: 10.1073/pnas.1208917109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869728 Free PMC article.
Sex effects in mouse prion disease incubation time.
Akhtar S, Wenborn A, Brandner S, Collinge J, Lloyd SE. Akhtar S, et al. Among authors: wenborn a. PLoS One. 2011;6(12):e28741. doi: 10.1371/journal.pone.0028741. Epub 2011 Dec 13. PLoS One. 2011. PMID: 22174884 Free PMC article.
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