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658 results

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Page 1
The rationale, design and baseline data of FLOW, a kidney outcomes trial with once-weekly semaglutide in people with type 2 diabetes and chronic kidney disease.
Rossing P, Baeres FMM, Bakris G, Bosch-Traberg H, Gislum M, Gough SCL, Idorn T, Lawson J, Mahaffey KW, Mann JFE, Mersebach H, Perkovic V, Tuttle K, Pratley R. Rossing P, et al. Among authors: mahaffey kw. Nephrol Dial Transplant. 2023 Aug 31;38(9):2041-2051. doi: 10.1093/ndt/gfad009. Nephrol Dial Transplant. 2023. PMID: 36651820 Free PMC article. Clinical Trial.
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy.
Perkovic V, Jardine MJ, Neal B, Bompoint S, Heerspink HJL, Charytan DM, Edwards R, Agarwal R, Bakris G, Bull S, Cannon CP, Capuano G, Chu PL, de Zeeuw D, Greene T, Levin A, Pollock C, Wheeler DC, Yavin Y, Zhang H, Zinman B, Meininger G, Brenner BM, Mahaffey KW; CREDENCE Trial Investigators. Perkovic V, et al. Among authors: mahaffey kw. N Engl J Med. 2019 Jun 13;380(24):2295-2306. doi: 10.1056/NEJMoa1811744. Epub 2019 Apr 14. N Engl J Med. 2019. PMID: 30990260 Free article. Clinical Trial.
Stroke-bleeding risk score pairings within individuals in the outcomes registry for better informed treatment of atrial fibrillation (ORBIT-AF) registry.
Jason MJ, Marzec LN, Piccini JP, Shrader P, Pieper KS, Blanco RG, Fonarow GC, Gersh BJ, Ho PM, Hylek E, Kowey PR, Mahaffey KW, Steinberg BA, Peterson ED, Allen LA. Jason MJ, et al. Among authors: mahaffey kw. Int J Cardiol. 2024 Dec 19:132912. doi: 10.1016/j.ijcard.2024.132912. Online ahead of print. Int J Cardiol. 2024. PMID: 39708904
The Coming AI Revolution in Clinical Trials.
Jain SS, Sarraju A, Shah NH, Schulman KA, Ashley EA, Harrington RA, Mahaffey KW. Jain SS, et al. Among authors: mahaffey kw. J Am Coll Cardiol. 2024 Nov 23:S0735-1097(24)10286-0. doi: 10.1016/j.jacc.2024.10.093. Online ahead of print. J Am Coll Cardiol. 2024. PMID: 39641738 No abstract available.
Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials.
Badve SV, Bilal A, Lee MMY, Sattar N, Gerstein HC, Ruff CT, McMurray JJV, Rossing P, Bakris G, Mahaffey KW, Mann JFE, Colhoun HM, Tuttle KR, Pratley RE, Perkovic V. Badve SV, et al. Among authors: mahaffey kw. Lancet Diabetes Endocrinol. 2024 Nov 25:S2213-8587(24)00271-7. doi: 10.1016/S2213-8587(24)00271-7. Online ahead of print. Lancet Diabetes Endocrinol. 2024. PMID: 39608381
Leveraging Deep Learning of Chest Radiograph Images to Identify Individuals at High Risk for Chronic Obstructive Pulmonary Disease.
Doroodgar Jorshery S, Chandra J, Walia AS, Stumiolo A, Corey K, Zekavat SM, Zinzuwadia AN, Patel K, Short S, Mega JL, Plowman RS, Pagidipati N, Sullivan SS, Mahaffey KW, Shah SH, Hernandez AF, Christiani D, Aerts HJWL, Weiss J, Lu MT, Raghu VK. Doroodgar Jorshery S, et al. Among authors: mahaffey kw. medRxiv [Preprint]. 2024 Nov 15:2024.11.14.24317055. doi: 10.1101/2024.11.14.24317055. medRxiv. 2024. PMID: 39606360 Free PMC article. Preprint.
Canagliflozin and iron metabolism in the CREDENCE trial.
Koshino A, Heerspink HJL, Jongs N, Badve SV, Arnott C, Neal B, Jardine M, Mahaffey KW, Pollock C, Perkovic V, Hansen MK, Bakker SJL, Wada T, Neuen BL. Koshino A, et al. Among authors: mahaffey kw. Nephrol Dial Transplant. 2024 Sep 20:gfae198. doi: 10.1093/ndt/gfae198. Online ahead of print. Nephrol Dial Transplant. 2024. PMID: 39304530
ApoA-I Infusions and Burden of Ischemic Events After Acute Myocardial Infarction: Insights From the AEGIS-II Trial.
Gibson CM, Chi G, Duffy D, Bahit MC, White H, Korjian S, Alexander JH, Lincoff AM, Anschuetz G, Girgis IG, Nicolau JC, Lopes RD, Cornel JH, Bainey KR, Libby P, Sacks FM, Ridker PM, Goodman SG, Mahaffey KW, Nicholls SJ, Pocock SJ, Mehran R, Harrington RA; AEGIS-II Committees and Investigators. Gibson CM, et al. Among authors: mahaffey kw. J Am Coll Cardiol. 2024 Nov 26;84(22):2185-2192. doi: 10.1016/j.jacc.2024.08.001. Epub 2024 Sep 2. J Am Coll Cardiol. 2024. PMID: 39230545 Clinical Trial.
Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials.
Kosiborod MN, Deanfield J, Pratley R, Borlaug BA, Butler J, Davies MJ, Emerson SS, Kahn SE, Kitzman DW, Lingvay I, Mahaffey KW, Petrie MC, Plutzky J, Rasmussen S, Rönnbäck C, Shah SJ, Verma S, Weeke PE, Lincoff AM; SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM Trial Committees and Investigators. Kosiborod MN, et al. Among authors: mahaffey kw. Lancet. 2024 Sep 7;404(10456):949-961. doi: 10.1016/S0140-6736(24)01643-X. Epub 2024 Aug 30. Lancet. 2024. PMID: 39222642 Clinical Trial.
658 results