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Page 1
BAP1 is a novel regulator of HIF-1α.
Bononi A, Wang Q, Zolondick AA, Bai F, Steele-Tanji M, Suarez JS, Pastorino S, Sipes A, Signorato V, Ferro A, Novelli F, Kim JH, Minaai M, Takinishi Y, Pellegrini L, Napolitano A, Xu R, Farrar C, Goparaju C, Bassi C, Negrini M, Pagano I, Sakamoto G, Gaudino G, Pass HI, Onuchic JN, Yang H, Carbone M. Bononi A, et al. Among authors: minaai m. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217840120. doi: 10.1073/pnas.2217840120. Epub 2023 Jan 19. Proc Natl Acad Sci U S A. 2023. PMID: 36656861 Free PMC article.
Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s.
Carbone M, Flores EG, Emi M, Johnson TA, Tsunoda T, Behner D, Hoffman H, Hesdorffer M, Nasu M, Napolitano A, Powers A, Minaai M, Baumann F, Bryant-Greenwood P, Lauk O, Kirschner MB, Weder W, Opitz I, Pass HI, Gaudino G, Pastorino S, Yang H. Carbone M, et al. Among authors: minaai m. PLoS Genet. 2015 Dec 18;11(12):e1005633. doi: 10.1371/journal.pgen.1005633. eCollection 2015 Dec. PLoS Genet. 2015. PMID: 26683624 Free PMC article.
A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of BAP1 and Other Germline Mutations.
Pastorino S, Yoshikawa Y, Pass HI, Emi M, Nasu M, Pagano I, Takinishi Y, Yamamoto R, Minaai M, Hashimoto-Tamaoki T, Ohmuraya M, Goto K, Goparaju C, Sarin KY, Tanji M, Bononi A, Napolitano A, Gaudino G, Hesdorffer M, Yang H, Carbone M. Pastorino S, et al. Among authors: minaai m. J Clin Oncol. 2018 Oct 30;36(35):JCO2018790352. doi: 10.1200/JCO.2018.79.0352. Online ahead of print. J Clin Oncol. 2018. PMID: 30376426 Free PMC article.
Mesothelioma: Scientific clues for prevention, diagnosis, and therapy.
Carbone M, Adusumilli PS, Alexander HR Jr, Baas P, Bardelli F, Bononi A, Bueno R, Felley-Bosco E, Galateau-Salle F, Jablons D, Mansfield AS, Minaai M, de Perrot M, Pesavento P, Rusch V, Severson DT, Taioli E, Tsao A, Woodard G, Yang H, Zauderer MG, Pass HI. Carbone M, et al. Among authors: minaai m. CA Cancer J Clin. 2019 Sep;69(5):402-429. doi: 10.3322/caac.21572. Epub 2019 Jul 8. CA Cancer J Clin. 2019. PMID: 31283845 Free PMC article. Review.
HMGB1 as a therapeutic target in disease.
Xue J, Suarez JS, Minaai M, Li S, Gaudino G, Pass HI, Carbone M, Yang H. Xue J, et al. Among authors: minaai m. J Cell Physiol. 2021 May;236(5):3406-3419. doi: 10.1002/jcp.30125. Epub 2020 Oct 26. J Cell Physiol. 2021. PMID: 33107103 Free PMC article. Review.
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma.
Bononi A, Goto K, Ak G, Yoshikawa Y, Emi M, Pastorino S, Carparelli L, Ferro A, Nasu M, Kim JH, Suarez JS, Xu R, Tanji M, Takinishi Y, Minaai M, Novelli F, Pagano I, Gaudino G, Pass HI, Groden J, Grzymski JJ, Metintas M, Akarsu M, Morrow B, Hassan R, Yang H, Carbone M. Bononi A, et al. Among authors: minaai m. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33466-33473. doi: 10.1073/pnas.2019652117. Epub 2020 Dec 14. Proc Natl Acad Sci U S A. 2020. PMID: 33318203 Free PMC article.
BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos.
Novelli F, Bononi A, Wang Q, Bai F, Patergnani S, Kricek F, Haglund E, Suarez JS, Tanji M, Xu R, Takanishi Y, Minaai M, Pastorino S, Morris P, Sakamoto G, Pass HI, Barbour H, Gaudino G, Giorgi C, Pinton P, Onuchic JN, Yang H, Carbone M. Novelli F, et al. Among authors: minaai m. Proc Natl Acad Sci U S A. 2021 Nov 30;118(48):e2111946118. doi: 10.1073/pnas.2111946118. Proc Natl Acad Sci U S A. 2021. PMID: 34815344 Free PMC article.
Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations.
Carbone M, Pass HI, Ak G, Alexander HR Jr, Baas P, Baumann F, Blakely AM, Bueno R, Bzura A, Cardillo G, Churpek JE, Dianzani I, De Rienzo A, Emi M, Emri S, Felley-Bosco E, Fennell DA, Flores RM, Grosso F, Hayward NK, Hesdorffer M, Hoang CD, Johansson PA, Kindler HL, Kittaneh M, Krausz T, Mansfield A, Metintas M, Minaai M, Mutti L, Nielsen M, O'Byrne K, Opitz I, Pastorino S, Pentimalli F, de Perrot M, Pritchard A, Ripley RT, Robinson B, Rusch V, Taioli E, Takinishi Y, Tanji M, Tsao AS, Tuncer AM, Walpole S, Wolf A, Yang H, Yoshikawa Y, Zolondick A, Schrump DS, Hassan R. Carbone M, et al. Among authors: minaai m. J Thorac Oncol. 2022 Jul;17(7):873-889. doi: 10.1016/j.jtho.2022.03.014. Epub 2022 Apr 21. J Thorac Oncol. 2022. PMID: 35462085 Free PMC article. Review.
HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma.
Suarez JS, Novelli F, Goto K, Ehara M, Steele M, Kim JH, Zolondick AA, Xue J, Xu R, Saito M, Pastorino S, Minaai M, Takanishi Y, Emi M, Pagano I, Wakeham A, Berger T, Pass HI, Gaudino G, Mak TW, Carbone M, Yang H. Suarez JS, et al. Among authors: minaai m. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2307999120. doi: 10.1073/pnas.2307999120. Epub 2023 Sep 20. Proc Natl Acad Sci U S A. 2023. PMID: 37729199 Free PMC article.
12 results