Savas JN - Search Results

1

The TgF344-AD rat: behavioral and proteomic changes associated with aging and protein expression in a transgenic rat model of Alzheimer's disease.

Bac B, Hicheri C, Weiss C, Buell A, Vilcek N, Spaeni C, Geula C, Savas JN, Disterhoft JF. Bac B, et al. Among authors: savas jn. Neurobiol Aging. 2023 Mar;123:98-110. doi: 10.1016/j.neurobiolaging.2022.12.015. Epub 2022 Dec 30. Neurobiol Aging. 2023. PMID: 36657371 Free PMC article.

2

Early developmental deletion of forebrain Ank2 causes seizure-related phenotypes by reshaping the synaptic proteome.

Yoon S, Santos MD, Forrest MP, Pratt CP, Khalatyan N, Mohler PJ, Savas JN, Penzes P. Yoon S, et al. Among authors: savas jn. Cell Rep. 2023 Jul 25;42(7):112784. doi: 10.1016/j.celrep.2023.112784. Epub 2023 Jul 9. Cell Rep. 2023. PMID: 37428632 Free PMC article.

3

The cochlea is built to last a lifetime.

Savas JN. Savas JN. Hear Res. 2023 Sep 1;436:108821. doi: 10.1016/j.heares.2023.108821. Epub 2023 Jun 1. Hear Res. 2023. PMID: 37295280 Free PMC article. Review.

4

Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan.

Bomba-Warczak EK, Velez KM, Zhou LT, Guillermier C, Edassery S, Steinhauser ML, Savas JN, Elizabeth Duncan F. Bomba-Warczak EK, et al. Among authors: savas jn. bioRxiv [Preprint]. 2024 Jul 5:2023.10.18.562852. doi: 10.1101/2023.10.18.562852. bioRxiv. 2024. Update in: Elife. 2024 Oct 31;13:RP93172. doi: 10.7554/eLife.93172 PMID: 37905022 Free PMC article. Updated. Preprint.

5

Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication.

Wang YZ, Castillon CCM, Gebis KK, Bartom ET, d'Azzo A, Contractor A, Savas JN. Wang YZ, et al. Among authors: savas jn. Cell Rep. 2024 Feb 27;43(2):113680. doi: 10.1016/j.celrep.2024.113680. Epub 2024 Jan 18. Cell Rep. 2024. PMID: 38241148 Free PMC article.

6

Leveraging biotin-based proximity labeling to identify cellular factors governing early alphaherpesvirus infection.

Quan J, Fan Q, Simons LM, Smukowski SN, Pegg C, Longnecker R, Savas JN, Hultquist JF, Smith GA. Quan J, et al. Among authors: savas jn. mBio. 2024 Aug 14;15(8):e0144524. doi: 10.1128/mbio.01445-24. Epub 2024 Jul 2. mBio. 2024. PMID: 38953638 Free PMC article.

7

Parkinson's disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons.

Song P, Peng W, Sauve V, Fakih R, Xie Z, Ysselstein D, Krainc T, Wong YC, Mencacci NE, Savas JN, Surmeier DJ, Gehring K, Krainc D. Song P, et al. Among authors: savas jn. Neuron. 2023 Dec 6;111(23):3775-3788.e7. doi: 10.1016/j.neuron.2023.08.018. Epub 2023 Sep 15. Neuron. 2023. PMID: 37716354 Free article.

8

A Pathogenic Missense Mutation in Kainate Receptors Elevates Dendritic Excitability and Synaptic Integration through Dysregulation of SK Channels.

Nomura T, Taniguchi S, Wang YZ, Yeh NH, Wilen AP, Castillon CCM, Foote KM, Xu J, Armstrong JN, Savas JN, Swanson GT, Contractor A. Nomura T, et al. Among authors: savas jn. J Neurosci. 2023 Nov 22;43(47):7913-7928. doi: 10.1523/JNEUROSCI.1259-23.2023. J Neurosci. 2023. PMID: 37802657 Free PMC article.

9

Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis.

Tsioras K, Smith KC, Edassery SL, Garjani M, Li Y, Williams C, McKenna ED, Guo W, Wilen AP, Hark TJ, Marklund SL, Ostrow LW, Gilthorpe JD, Ichida JK, Kalb RG, Savas JN, Kiskinis E. Tsioras K, et al. Among authors: savas jn. Cell Rep. 2023 Oct 31;42(10):113160. doi: 10.1016/j.celrep.2023.113160. Epub 2023 Sep 29. Cell Rep. 2023. PMID: 37776851 Free PMC article.

10

Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins.

Cardanho-Ramos C, Simões RA, Wang YZ, Faria-Pereira A, Bomba-Warczak E, Craessaerts K, Spinazzi M, Savas JN, Morais VA. Cardanho-Ramos C, et al. Among authors: savas jn. iScience. 2024 Feb 5;27(4):109136. doi: 10.1016/j.isci.2024.109136. eCollection 2024 Apr 19. iScience. 2024. PMID: 38510136 Free PMC article.

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