Jacobs H - Search Results

1

Mammalian life depends on two distinct pathways of DNA damage tolerance.

Buoninfante OA, Pilzecker B, Spanjaard A, de Groot D, Prekovic S, Song JY, Lieftink C, Ayidah M, Pritchard CEJ, Vivié J, Mcgrath KE, Huijbers IJ, Philipsen S, von Lindern M, Zwart W, Beijersbergen RL, Palis J, van den Berk PCM, Jacobs H. Buoninfante OA, et al. Among authors: jacobs h. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2216055120. doi: 10.1073/pnas.2216055120. Epub 2023 Jan 20. Proc Natl Acad Sci U S A. 2023. PMID: 36669105 Free PMC article.

2

Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice.

Jansen JG, Langerak P, Tsaalbi-Shtylik A, van den Berk P, Jacobs H, de Wind N. Jansen JG, et al. Among authors: jacobs h. J Exp Med. 2006 Feb 20;203(2):319-23. doi: 10.1084/jem.20052227. Epub 2006 Feb 13. J Exp Med. 2006. PMID: 16476771 Free PMC article.

3

Gimap4 accelerates T-cell death.

Schnell S, Démollière C, van den Berk P, Jacobs H. Schnell S, et al. Among authors: jacobs h. Blood. 2006 Jul 15;108(2):591-9. doi: 10.1182/blood-2005-11-4616. Epub 2006 Mar 28. Blood. 2006. PMID: 16569770 Free article.

4

Constitutive expression of the pre-TCR enables development of mature T cells.

Schnell S, Démollière C, van den Berk P, Kirberg J, Jacobs H. Schnell S, et al. Among authors: jacobs h. Int Immunol. 2006 Jun;18(6):911-20. doi: 10.1093/intimm/dxl028. Epub 2006 Apr 26. Int Immunol. 2006. PMID: 16641111

5

A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification.

Langerak P, Nygren AO, Krijger PH, van den Berk PC, Jacobs H. Langerak P, et al. Among authors: jacobs h. J Exp Med. 2007 Aug 6;204(8):1989-98. doi: 10.1084/jem.20070902. Epub 2007 Jul 30. J Exp Med. 2007. PMID: 17664295 Free PMC article.

6

Somatic hypermutation of immunoglobulin genes: lessons from proliferating cell nuclear antigenK164R mutant mice.

Langerak P, Krijger PH, Heideman MR, van den Berk PC, Jacobs H. Langerak P, et al. Among authors: jacobs h. Philos Trans R Soc Lond B Biol Sci. 2009 Mar 12;364(1517):621-9. doi: 10.1098/rstb.2008.0223. Philos Trans R Soc Lond B Biol Sci. 2009. PMID: 19008189 Free PMC article.

7

Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.

Middendorp S, Xiao Y, Song JY, Peperzak V, Krijger PH, Jacobs H, Borst J. Middendorp S, et al. Among authors: jacobs h. Blood. 2009 Sep 10;114(11):2280-9. doi: 10.1182/blood-2009-03-208215. Epub 2009 Jul 16. Blood. 2009. PMID: 19608748 Free article.

8

Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.

Krijger PH, Langerak P, van den Berk PC, Jacobs H. Krijger PH, et al. Among authors: jacobs h. J Exp Med. 2009 Nov 23;206(12):2603-11. doi: 10.1084/jem.20091707. Epub 2009 Nov 9. J Exp Med. 2009. PMID: 19901081 Free PMC article.

9

The Fanconi anemia core complex is dispensable during somatic hypermutation and class switch recombination.

Krijger PH, Wit N, van den Berk PC, Jacobs H. Krijger PH, et al. Among authors: jacobs h. PLoS One. 2010 Dec 29;5(12):e15236. doi: 10.1371/journal.pone.0015236. PLoS One. 2010. PMID: 21209924 Free PMC article.

10

HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: existence of an alternative E3 ligase.

Krijger PH, Lee KY, Wit N, van den Berk PC, Wu X, Roest HP, Maas A, Ding H, Hoeijmakers JH, Myung K, Jacobs H. Krijger PH, et al. Among authors: jacobs h. DNA Repair (Amst). 2011 Apr 3;10(4):438-44. doi: 10.1016/j.dnarep.2010.12.008. Epub 2011 Jan 26. DNA Repair (Amst). 2011. PMID: 21269891 Free PMC article.

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