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331 results

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Base editing screens map mutations affecting interferon-γ signaling in cancer.
Coelho MA, Cooper S, Strauss ME, Karakoc E, Bhosle S, Gonçalves E, Picco G, Burgold T, Cattaneo CM, Veninga V, Consonni S, Dinçer C, Vieira SF, Gibson F, Barthorpe S, Hardy C, Rein J, Thomas M, Marioni J, Voest EE, Bassett A, Garnett MJ. Coelho MA, et al. Among authors: voest ee. Cancer Cell. 2023 Feb 13;41(2):288-303.e6. doi: 10.1016/j.ccell.2022.12.009. Epub 2023 Jan 19. Cancer Cell. 2023. PMID: 36669486 Free PMC article.
Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity.
Vennin C, Cattaneo CM, Bosch L, Vegna S, Ma X, Damstra HGJ, Martinovic M, Tsouri E, Ilic M, Azarang L, van Weering JRT, Pulver E, Zeeman AL, Schelfhorst T, Lohuis JO, Rios AC, Dekkers JF, Akkari L, Menezes R, Medema R, Baglio SR, Akhmanova A, Linn SC, Lemeer S, Pegtel DM, Voest EE, van Rheenen J. Vennin C, et al. Among authors: voest ee. Cancer Cell. 2023 Jun 12;41(6):1170-1185.e12. doi: 10.1016/j.ccell.2023.05.009. Cancer Cell. 2023. PMID: 37311414 Free article.
A pan-cancer analysis of the microbiome in metastatic cancer.
Battaglia TW, Mimpen IL, Traets JJH, van Hoeck A, Zeverijn LJ, Geurts BS, de Wit GF, Noë M, Hofland I, Vos JL, Cornelissen S, Alkemade M, Broeks A, Zuur CL, Cuppen E, Wessels L, van de Haar J, Voest E. Battaglia TW, et al. Cell. 2024 Apr 25;187(9):2324-2335.e19. doi: 10.1016/j.cell.2024.03.021. Epub 2024 Apr 9. Cell. 2024. PMID: 38599211 Free article.
Trastuzumab plus pertuzumab for HER2-amplified advanced colorectal cancer: Results from the drug rediscovery protocol (DRUP).
Spiekman IAC, Zeverijn LJ, Geurts BS, Verkerk K, Haj Mohammad SF, van der Noort V, Roepman P, de Leng WWJ, Jansen AML, Gootjes EC, de Groot DA, Kerver ED, van Voorthuizen T, Roodhart JML, Valkenburg-van Iersel LBJ, Gelderblom H, Voest EE, Verheul HMW. Spiekman IAC, et al. Among authors: voest ee. Eur J Cancer. 2024 May;202:113988. doi: 10.1016/j.ejca.2024.113988. Epub 2024 Mar 7. Eur J Cancer. 2024. PMID: 38471288 Free article.
Agnostic drug development revisited.
Hernando-Calvo A, Rossi A, Vieito M, Voest E, Garralda E. Hernando-Calvo A, et al. Cancer Treat Rev. 2024 Jul;128:102747. doi: 10.1016/j.ctrv.2024.102747. Epub 2024 Apr 27. Cancer Treat Rev. 2024. PMID: 38763053 Review.
The pathway alteration load is a pan-cancer determinant of outcome of targeted therapies: results from the Drug Rediscovery Protocol (DRUP).
Verkerk K, Zeverijn LJ, van de Haar J, Roepman P, Geurts BS, Spiekman AC, van der Noort V, van Berge Henegouwen JM, Hoes LR, van der Wijngaart H, Jansen AML, de Leng WWJ, Gelderblom AJ, Verheul HMW, Voest EE. Verkerk K, et al. Among authors: voest ee. ESMO Open. 2025 Jan 7;10(1):104112. doi: 10.1016/j.esmoop.2024.104112. Online ahead of print. ESMO Open. 2025. PMID: 39778224 Free article.
Base editing screens define the genetic landscape of cancer drug resistance mechanisms.
Coelho MA, Strauss ME, Watterson A, Cooper S, Bhosle S, Illuzzi G, Karakoc E, Dinçer C, Vieira SF, Sharma M, Moullet M, Conticelli D, Koeppel J, McCarten K, Cattaneo CM, Veninga V, Picco G, Parts L, Forment JV, Voest EE, Marioni JC, Bassett A, Garnett MJ. Coelho MA, et al. Among authors: voest ee. Nat Genet. 2024 Nov;56(11):2479-2492. doi: 10.1038/s41588-024-01948-8. Epub 2024 Oct 18. Nat Genet. 2024. PMID: 39424923 Free PMC article.
331 results