Chen JF - Search Results

1

Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis.

Pei F, Ma L, Jing J, Feng J, Yuan Y, Guo T, Han X, Ho TV, Lei J, He J, Zhang M, Chen JF, Chai Y. Pei F, et al. Among authors: chen jf. Nat Commun. 2023 Jan 20;14(1):344. doi: 10.1038/s41467-023-35977-4. Nat Commun. 2023. PMID: 36670126 Free PMC article.

2

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult.

Herrlinger SA, Shao Q, Ma L, Brindley M, Chen JF. Herrlinger SA, et al. Among authors: chen jf. J Vis Exp. 2018 Apr 26;(134):56486. doi: 10.3791/56486. J Vis Exp. 2018. PMID: 29757270 Free PMC article.

3

Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors.

Zhang W, Yang SL, Yang M, Herrlinger S, Shao Q, Collar JL, Fierro E, Shi Y, Liu A, Lu H, Herring BE, Guo ML, Buch S, Zhao Z, Xu J, Lu Z, Chen JF. Zhang W, et al. Among authors: chen jf. Nat Commun. 2019 Jun 13;10(1):2612. doi: 10.1038/s41467-019-10497-2. Nat Commun. 2019. PMID: 31197141 Free PMC article.

4

C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis.

Shao Q, Yang M, Liang C, Ma L, Zhang W, Jiang Z, Luo J, Lee JK, Liang C, Chen JF. Shao Q, et al. Among authors: chen jf. Autophagy. 2020 Sep;16(9):1635-1650. doi: 10.1080/15548627.2019.1703353. Epub 2019 Dec 26. Autophagy. 2020. PMID: 31847700 Free PMC article.

5

Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes.

Zhang W, Ma L, Yang M, Shao Q, Xu J, Lu Z, Zhao Z, Chen R, Chai Y, Chen JF. Zhang W, et al. Among authors: chen r, chen jf. Genes Dev. 2020 Apr 1;34(7-8):580-597. doi: 10.1101/gad.332494.119. Epub 2020 Feb 27. Genes Dev. 2020. PMID: 32115408 Free PMC article.

6

Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis.

Yu M, Ma L, Yuan Y, Ye X, Montagne A, He J, Ho TV, Wu Y, Zhao Z, Sta Maria N, Jacobs R, Urata M, Wang H, Zlokovic BV, Chen JF, Chai Y. Yu M, et al. Among authors: chen jf. Cell. 2021 Jan 7;184(1):243-256.e18. doi: 10.1016/j.cell.2020.11.037. Cell. 2021. PMID: 33417861 Free PMC article.

7

Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases.

Zhang M, Li K, Bai J, Velema WA, Yu C, van Damme R, Lee WH, Corpuz ML, Chen JF, Lu Z. Zhang M, et al. Among authors: chen jf. Nat Commun. 2021 Apr 20;12(1):2344. doi: 10.1038/s41467-021-22552-y. Nat Commun. 2021. PMID: 33879794 Free PMC article.

8

Reversing neural circuit and behavior deficit in mice exposed to maternal inflammation by Zika virus.

Ma L, Wang J, Ge J, Wang Y, Zhang W, Du Y, Luo J, Li Y, Wang F, Fan G, Chen R, Yao B, Zhao Z, Guo ML, Kim WK, Chai Y, Chen JF. Ma L, et al. Among authors: chen r, chen jf. EMBO Rep. 2021 Aug 4;22(8):e51978. doi: 10.15252/embr.202051978. Epub 2021 Jul 7. EMBO Rep. 2021. PMID: 34232545 Free PMC article.

9

The clinical manifestations, molecular mechanisms and treatment of craniosynostosis.

Stanton E, Urata M, Chen JF, Chai Y. Stanton E, et al. Among authors: chen jf. Dis Model Mech. 2022 Apr 1;15(4):dmm049390. doi: 10.1242/dmm.049390. Epub 2022 Apr 22. Dis Model Mech. 2022. PMID: 35451466 Free PMC article. Review.

10

Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors.

Ma L, Liang C, Wang J, Chang Q, Wang Y, Zhang W, Du Y, Sadan J, Chen JF. Ma L, et al. Among authors: chen jf. Hum Mol Genet. 2023 Apr 6;32(8):1252-1265. doi: 10.1093/hmg/ddac271. Hum Mol Genet. 2023. PMID: 36322143 Free PMC article.

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