Ibrahim IM - Search Results

1

A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study.

Eissa IH, Yousef RG, Elkady H, Alsfouk AA, Alsfouk BA, Husein DZ, Ibrahim IM, Elkaeed EB, Metwaly AM. Eissa IH, et al. Among authors: ibrahim im. Life (Basel). 2023 Jan 9;13(1):191. doi: 10.3390/life13010191. Life (Basel). 2023. PMID: 36676140 Free PMC article.

2

Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects.

Elkaeed EB, Yousef RG, Elkady H, Gobaara IMM, Alsfouk BA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Elkaeed EB, et al. Among authors: ibrahim im. Molecules. 2022 Jul 19;27(14):4606. doi: 10.3390/molecules27144606. Molecules. 2022. PMID: 35889478 Free PMC article.

3

Discovery of new 1H-pyrazolo[3,4-d]pyrimidine derivatives as anticancer agents targeting EGFR^WT and EGFR^T790M.

Gaber AA, Sobhy M, Turky A, Abdulwahab HG, Al-Karmalawy AA, Elhendawy MA, Radwan MM, Elkaeed EB, Ibrahim IM, Elzahabi HSA, Eissa IH. Gaber AA, et al. Among authors: ibrahim im. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2283-2303. doi: 10.1080/14756366.2022.2112575. J Enzyme Inhib Med Chem. 2022. PMID: 36000168 Free PMC article.

4

New Anticancer Theobromine Derivative Targeting EGFR^WT and EGFR^T790M: Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies.

Elkaeed EB, Yousef RG, Elkady H, Alsfouk AA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Elkaeed EB, et al. Among authors: ibrahim im. Molecules. 2022 Sep 9;27(18):5859. doi: 10.3390/molecules27185859. Molecules. 2022. PMID: 36144596 Free PMC article.

5

In silico, in vitro VEGFR-2 inhibition, and anticancer activity of a 3-(hydrazonomethyl)naphthalene-2-ol derivative.

Elkaeed EB, Yousef RG, Elkady H, Mehany ABM, Alsfouk BA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Elkaeed EB, et al. Among authors: ibrahim im. J Biomol Struct Dyn. 2023 Sep-Oct;41(16):7986-8001. doi: 10.1080/07391102.2022.2127907. Epub 2022 Oct 2. J Biomol Struct Dyn. 2023. PMID: 36184591

6

(E)-N-(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: Synthesis, Computational, and Anticancer Studies.

Yousef RG, Elkady H, Elkaeed EB, Gobaara IMM, Al-Ghulikah HA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Yousef RG, et al. Among authors: ibrahim im. Molecules. 2022 Nov 9;27(22):7719. doi: 10.3390/molecules27227719. Molecules. 2022. PMID: 36431818 Free PMC article.

7

New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies.

Gaber AA, Sobhy M, Turky A, Eldehna WM, El-Sebaey SA, El-Metwally SA, El-Naggar AM, Ibrahim IM, Elkaeed EB, Metwaly AM, Eissa IH. Gaber AA, et al. Among authors: ibrahim im. PLoS One. 2023 Jan 30;18(1):e0274081. doi: 10.1371/journal.pone.0274081. eCollection 2023. PLoS One. 2023. PMID: 36716311 Free PMC article.

8

Computer-assisted drug discovery of potential natural inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase through a multi-phase in silico approach.

Elkaeed EB, Alsfouk BA, Ibrahim TH, Arafa RK, Elkady H, Ibrahim IM, Eissa IH, Metwaly AM. Elkaeed EB, et al. Among authors: ibrahim th, ibrahim im. Antivir Ther. 2023 Oct;28(5):13596535231199838. doi: 10.1177/13596535231199838. Antivir Ther. 2023. PMID: 37669909 Free article.

9

Integrated study of Quercetin as a potent SARS-CoV-2 RdRp inhibitor: Binding interactions, MD simulations, and In vitro assays.

Metwaly AM, El-Fakharany EM, Alsfouk AA, Ibrahim IM, Elkaeed EB, Eissa IH. Metwaly AM, et al. Among authors: ibrahim im. PLoS One. 2024 Dec 3;19(12):e0312866. doi: 10.1371/journal.pone.0312866. eCollection 2024. PLoS One. 2024. PMID: 39625895 Free PMC article.

10

Repurposing FDA-approved drugs for COVID-19: targeting the main protease through multi-phase in silico approach.

Metwaly AM, Elkaeed EB, Alsfouk AA, Ibrahim IM, Elkady H, Eissa IH. Metwaly AM, et al. Among authors: ibrahim im. Antivir Ther. 2024 Dec;29(6):13596535241305536. doi: 10.1177/13596535241305536. Antivir Ther. 2024. PMID: 39639531 Free article.

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