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Optimization of a micro-scale air-liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2.
Sen C, Rickabaugh TM, Jeyachandran AV, Yuen C, Ghannam M, Durra A, Aziz A, Castillo K, Garcia G Jr, Purkayastha A, Han B, Boulton FW, Chekler E, Garces R, Wolff KC, Riva L, Kirkpatrick MG, Gebara-Lamb A, McNamara CW, Betz UAK, Arumugaswami V, Damoiseaux R, Gomperts BN. Sen C, et al. Among authors: garcia g jr. Respir Res. 2025 Jan 16;26(1):18. doi: 10.1186/s12931-025-03095-y. Respir Res. 2025. PMID: 39819574
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.
Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: garcia g jr. Nat Commun. 2023 Apr 25;14(1):2379. doi: 10.1038/s41467-023-37865-3. Nat Commun. 2023. PMID: 37185252 Free PMC article.
Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses.
Garcia G Jr, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Castillo Cario S, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells MS, Ramaiah A, Arumugaswami V. Garcia G Jr, et al. Cell Rep Med. 2023 May 16;4(5):101024. doi: 10.1016/j.xcrm.2023.101024. Epub 2023 Apr 28. Cell Rep Med. 2023. PMID: 37119814 Free PMC article.
Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses.
Garcia G Jr, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Cario SC, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells M, Ramaiah A, Arumugaswami V. Garcia G Jr, et al. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524824. doi: 10.1101/2023.01.19.524824. bioRxiv. 2023. Update in: Cell Rep Med. 2023 May 16;4(5):101024. doi: 10.1016/j.xcrm.2023.101024 PMID: 36711787 Free PMC article. Updated. Preprint.
Differential Susceptibility of Fetal Retinal Pigment Epithelial Cells, hiPSC- Retinal Stem Cells, and Retinal Organoids to Zika Virus Infection.
Contreras D, Garcia G Jr, Jones MK, Martinez LE, Jayakarunakaran A, Gangalapudi V, Tang J, Wu Y, Zhao JJ, Chen Z, Ramaiah A, Tsui I, Kumar A, Nielsen-Saines K, Wang S, Arumugaswami V. Contreras D, et al. Among authors: garcia g jr. Viruses. 2023 Jan 1;15(1):142. doi: 10.3390/v15010142. Viruses. 2023. PMID: 36680182 Free PMC article.
45 results