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First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2.
Smit MJ, Sander AF, Ariaans MBPA, Fougeroux C, Heinzel C, Fendel R, Esen M, Kremsner PG, Ter Heine R, Wertheim HF, Idorn M, Paludan SR, Underwood AP, Binderup A, Ramirez S, Bukh J, Soegaard M, Erdogan SM, Gustavsson T, Clemmensen S, Theander TG, Salanti A, Hamborg M, de Jongh WA, McCall MBB, Nielsen MA, Mordmüller BG; COUGH-1 trial study group. Smit MJ, et al. Among authors: bukh j. Lancet Microbe. 2023 Mar;4(3):e140-e148. doi: 10.1016/S2666-5247(22)00337-8. Epub 2023 Jan 18. Lancet Microbe. 2023. PMID: 36681093 Free PMC article. Clinical Trial.
Durability and breadth of neutralisation following multiple antigen exposures to SARS-CoV-2 infection and/or COVID-19 vaccination.
Underwood AP, Sølund C, Fernandez-Antunez C, Villadsen SL, Mikkelsen LS, Fahnøe U, Bollerup S, Winckelmann AA, Schneider UV, Binderup A, Vizgirda G, Sørensen AL, Vinten CN, Dalegaard MI, Ramirez S, Weis N, Bukh J. Underwood AP, et al. Among authors: bukh j. EBioMedicine. 2023 Mar;89:104475. doi: 10.1016/j.ebiom.2023.104475. Epub 2023 Mar 2. EBioMedicine. 2023. PMID: 36870117 Free PMC article.
Neutralizing antibody and CD8+ T cell responses following BA.4/5 bivalent COVID-19 booster vaccination in adults with and without prior exposure to SARS-CoV-2.
Underwood AP, Sølund C, Jacobsen K, Binderup A, Fernandez-Antunez C, Mikkelsen LS, Inekci D, Villadsen SL, Castruita JAS, Pinholt M, Fahnøe U, Ramirez S, Brix L, Weis N, Bukh J. Underwood AP, et al. Among authors: bukh j. Front Immunol. 2024 Mar 20;15:1353353. doi: 10.3389/fimmu.2024.1353353. eCollection 2024. Front Immunol. 2024. PMID: 38571939 Free PMC article.
An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals.
Offersgaard A, Duarte Hernandez CR, Zhou Y, Duan Z, Gammeltoft KA, Hartmann KT, Fahnøe U, Marichal-Gallardo P, Alzua GP, Underwood AP, Sølund C, Weis N, Bonde JH, Christensen JP, Pedersen GK, Jensen HE, Holmbeck K, Bukh J, Gottwein JM. Offersgaard A, et al. Among authors: bukh j. Sci Rep. 2024 Jul 24;14(1):17039. doi: 10.1038/s41598-024-67570-0. Sci Rep. 2024. PMID: 39048693 Free PMC article.
Neutralisation resistance of SARS-CoV-2 spike-variants is primarily mediated by synergistic receptor binding domain substitutions.
Pham LV, Underwood AP, Binderup A, Fahnøe U, Fernandez-Antunez C, Lopez-Mendez B, Ryberg LA, Galli A, Sølund C, Weis N, Ramirez S, Bukh J. Pham LV, et al. Among authors: bukh j. Emerg Microbes Infect. 2024 Dec;13(1):2412643. doi: 10.1080/22221751.2024.2412643. Epub 2024 Nov 13. Emerg Microbes Infect. 2024. PMID: 39392057 Free PMC article.
B-cell characteristics define HCV reinfection outcome.
Underwood AP, Gupta M, Wu BR, Eltahla AA, Boo I, Wang JJ, Agapiou D, Abayasingam A, Reynaldi A, Keoshkerian E, Zhao Y, Brasher N, Walker MR, Bukh J, Maher L, Gordon T, Davenport MP, Luciani F, Drummer HE, Lloyd AR, Bull RA. Underwood AP, et al. Among authors: bukh j. J Hepatol. 2024 Sep;81(3):415-428. doi: 10.1016/j.jhep.2024.04.004. Epub 2024 Apr 10. J Hepatol. 2024. PMID: 38604387 Free article.
Hepatitis C virus alters the morphology and function of peroxisomes.
Martin de Fourchambault E, Callens N, Saliou JM, Fourcot M, Delos O, Barois N, Thorel Q, Ramirez S, Bukh J, Cocquerel L, Bertrand-Michel J, Marot G, Sebti Y, Dubuisson J, Rouillé Y. Martin de Fourchambault E, et al. Among authors: bukh j. Front Microbiol. 2023 Sep 21;14:1254728. doi: 10.3389/fmicb.2023.1254728. eCollection 2023. Front Microbiol. 2023. PMID: 37808318 Free PMC article.
317 results