Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function.
Wang B, Wang L, Gasek NS, Kuo CL, Nie J, Kim T, Yan P, Zhu J, Torrance BL, Zhou Y, Flores LC, Allen C, Andrade AM, Guo C, Cohn RL, Jellison ER, Bartley JM, Kuchel GA, Li S, Pirtskhalava T, Tchkonia T, Yadav S, Haynes L, Kirkland JL, Ikeno Y, Xu M.
Wang B, et al. Among authors: kuchel ga.
Cell Metab. 2024 Aug 6;36(8):1795-1805.e6. doi: 10.1016/j.cmet.2024.07.006.
Cell Metab. 2024.
PMID: 39111286