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Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and suppresses autoimmunity.
Zhang B, Sun J, Yuan Y, Ji D, Sun Y, Liu Y, Li S, Zhu X, Wu X, Hu J, Xie Q, Wu L, Liu L, Cheng B, Zhang Y, Jiang L, Zhao L, Yu F, Song W, Wang M, Xu Y, Ma S, Fei Y, Zhang L, Zhou D, Zhang X. Zhang B, et al. Among authors: zhang l, zhang x, zhang y. Signal Transduct Target Ther. 2023 Jan 23;8(1):28. doi: 10.1038/s41392-022-01208-3. Signal Transduct Target Ther. 2023. PMID: 36690610 Free PMC article.
CARs: a new approach for the treatment of autoimmune diseases.
Sun Y, Yuan Y, Zhang B, Zhang X. Sun Y, et al. Among authors: zhang b, zhang x. Sci China Life Sci. 2023 Apr;66(4):711-728. doi: 10.1007/s11427-022-2212-5. Epub 2022 Nov 4. Sci China Life Sci. 2023. PMID: 36346550 Free PMC article. Review.
Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity.
Xu H, Zhang X, Wang X, Li B, Yu H, Quan Y, Jiang Y, You Y, Wang Y, Wen M, Liu J, Wang M, Zhang B, Li Y, Zhang X, Lu Q, Yu CY, Cao X. Xu H, et al. Among authors: zhang b, zhang x. Immunity. 2024 Aug 13;57(8):1796-1811.e8. doi: 10.1016/j.immuni.2024.05.025. Epub 2024 Jun 21. Immunity. 2024. PMID: 38908373
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