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PROKR2 mutations in idiopathic hypogonadotropic hypogonadism: selective disruption of the binding to a Gα-protein leads to biased signaling.
Zhao Y, Wu J, Jia H, Wang X, Zheng R, Jiang F, Chen DN, Chen Z, Li JD. Zhao Y, et al. Among authors: zheng r. FASEB J. 2019 Mar;33(3):4538-4546. doi: 10.1096/fj.201801575R. Epub 2018 Dec 21. FASEB J. 2019. PMID: 30576231
Our results indicated that selective disruption of the interaction with a specific Galpha-protein might underlie the biased signaling for certain IHH-associated PROKR2 mutations.-Zhao, Y., Wu, J., Jia, H., Wang, X., Zheng, R., Jiang, F., Chen, D.-N., Chen, Z., Li, J …
Our results indicated that selective disruption of the interaction with a specific Galpha-protein might underlie the biased signaling for ce …
4,664 results