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Insulin-regulated serine and lipid metabolism drive peripheral neuropathy.
Handzlik MK, Gengatharan JM, Frizzi KE, McGregor GH, Martino C, Rahman G, Gonzalez A, Moreno AM, Green CR, Guernsey LS, Lin T, Tseng P, Ideguchi Y, Fallon RJ, Chaix A, Panda S, Mali P, Wallace M, Knight R, Gantner ML, Calcutt NA, Metallo CM. Handzlik MK, et al. Among authors: moreno am. Nature. 2023 Feb;614(7946):118-124. doi: 10.1038/s41586-022-05637-6. Epub 2023 Jan 25. Nature. 2023. PMID: 36697822 Free PMC article.
Therapeutic genome engineering via CRISPR-Cas systems.
Moreno AM, Mali P. Moreno AM, et al. Wiley Interdiscip Rev Syst Biol Med. 2017 Jul;9(4). doi: 10.1002/wsbm.1380. Epub 2017 Feb 15. Wiley Interdiscip Rev Syst Biol Med. 2017. PMID: 28198142 Review.
In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation.
Moreno AM, Fu X, Zhu J, Katrekar D, Shih YV, Marlett J, Cabotaje J, Tat J, Naughton J, Lisowski L, Varghese S, Zhang K, Mali P. Moreno AM, et al. Mol Ther. 2018 Jul 5;26(7):1818-1827. doi: 10.1016/j.ymthe.2018.04.017. Epub 2018 Apr 25. Mol Ther. 2018. PMID: 29754775 Free PMC article.
Long-lasting analgesia via targeted in situ repression of NaV1.7 in mice.
Moreno AM, Alemán F, Catroli GF, Hunt M, Hu M, Dailamy A, Pla A, Woller SA, Palmer N, Parekh U, McDonald D, Roberts AJ, Goodwill V, Dryden I, Hevner RF, Delay L, Gonçalves Dos Santos G, Yaksh TL, Mali P. Moreno AM, et al. Sci Transl Med. 2021 Mar 10;13(584):eaay9056. doi: 10.1126/scitranslmed.aay9056. Sci Transl Med. 2021. PMID: 33692134 Free PMC article.
In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation.
Moreno AM, Fu X, Zhu J, Katrekar D, Shih YV, Marlett J, Cabotaje J, Tat J, Naughton J, Lisowski L, Varghese S, Zhang K, Mali P. Moreno AM, et al. Mol Ther. 2020 Aug 5;28(8):1931. doi: 10.1016/j.ymthe.2020.06.027. Epub 2020 Jun 29. Mol Ther. 2020. PMID: 32603653 Free PMC article. No abstract available.
218 results