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Insulin-regulated serine and lipid metabolism drive peripheral neuropathy.
Handzlik MK, Gengatharan JM, Frizzi KE, McGregor GH, Martino C, Rahman G, Gonzalez A, Moreno AM, Green CR, Guernsey LS, Lin T, Tseng P, Ideguchi Y, Fallon RJ, Chaix A, Panda S, Mali P, Wallace M, Knight R, Gantner ML, Calcutt NA, Metallo CM. Handzlik MK, et al. Among authors: wallace m. Nature. 2023 Feb;614(7946):118-124. doi: 10.1038/s41586-022-05637-6. Epub 2023 Jan 25. Nature. 2023. PMID: 36697822 Free PMC article.
Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.
Svensson RU, Parker SJ, Eichner LJ, Kolar MJ, Wallace M, Brun SN, Lombardo PS, Van Nostrand JL, Hutchins A, Vera L, Gerken L, Greenwood J, Bhat S, Harriman G, Westlin WF, Harwood HJ Jr, Saghatelian A, Kapeller R, Metallo CM, Shaw RJ. Svensson RU, et al. Among authors: wallace m. Nat Med. 2016 Oct;22(10):1108-1119. doi: 10.1038/nm.4181. Epub 2016 Sep 19. Nat Med. 2016. PMID: 27643638 Free PMC article.
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.
Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, Metallo CM, Snyder NW, Andrews AJ, Wellen KE. Zhao S, et al. Among authors: wallace m. Cell Rep. 2016 Oct 18;17(4):1037-1052. doi: 10.1016/j.celrep.2016.09.069. Cell Rep. 2016. PMID: 27760311 Free PMC article.
CRY2 and FBXL3 Cooperatively Degrade c-MYC.
Huber AL, Papp SJ, Chan AB, Henriksson E, Jordan SD, Kriebs A, Nguyen M, Wallace M, Li Z, Metallo CM, Lamia KA. Huber AL, et al. Among authors: wallace m. Mol Cell. 2016 Nov 17;64(4):774-789. doi: 10.1016/j.molcel.2016.10.012. Epub 2016 Nov 10. Mol Cell. 2016. PMID: 27840026 Free PMC article.
Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death.
Divakaruni AS, Wallace M, Buren C, Martyniuk K, Andreyev AY, Li E, Fields JA, Cordes T, Reynolds IJ, Bloodgood BL, Raymond LA, Metallo CM, Murphy AN. Divakaruni AS, et al. Among authors: wallace m. J Cell Biol. 2017 Apr 3;216(4):1091-1105. doi: 10.1083/jcb.201612067. Epub 2017 Mar 2. J Cell Biol. 2017. PMID: 28254829 Free PMC article.
Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis.
Sanchez-Gurmaches J, Tang Y, Jespersen NZ, Wallace M, Martinez Calejman C, Gujja S, Li H, Edwards YJK, Wolfrum C, Metallo CM, Nielsen S, Scheele C, Guertin DA. Sanchez-Gurmaches J, et al. Among authors: wallace m. Cell Metab. 2018 Jan 9;27(1):195-209.e6. doi: 10.1016/j.cmet.2017.10.008. Epub 2017 Nov 16. Cell Metab. 2018. PMID: 29153407 Free PMC article.
3,774 results