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Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization.
Damaskinaki FN, Jooss NJ, Martin EM, Clark JC, Thomas MR, Poulter NS, Emsley J, Kellam B, Watson SP, Slater A. Damaskinaki FN, et al. Among authors: emsley j. J Thromb Haemost. 2023 Feb;21(2):317-328. doi: 10.1016/j.jtha.2022.11.002. Epub 2022 Dec 22. J Thromb Haemost. 2023. PMID: 36700508 Free article.
Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections.
Soukarieh F, Mashabi A, Richardson W, Oton EV, Romero M, Dubern JF, Robertson SN, Lucanto S, Markham-Lee Z, Sou T, Kukavica-Ibrulj I, Levesque RC, Bergstrom CAS, Halliday N, Kellam B, Emsley J, Heeb S, Williams P, Stocks MJ, Cámara M. Soukarieh F, et al. Among authors: emsley j. J Med Chem. 2024 Jan 25;67(2):1008-1023. doi: 10.1021/acs.jmedchem.3c00973. Epub 2024 Jan 3. J Med Chem. 2024. PMID: 38170170 Free PMC article.
Epithelial Interleukin-1 Receptor-Like-1 Activation Is Contingent on Interleukin-33 Isoforms and Asthma-Related Receptor Variation.
Portelli MA, Ketelaar ME, Bates S, Csomor E, Shaw D, Emsley J, Brightling C, Hall I, Affleck K, Edwards M, Nawijn MC, Koppelman GH, Van Oosterhout AJ, Sayers I. Portelli MA, et al. Among authors: emsley j. Clin Exp Allergy. 2024 Dec;54(12):984-995. doi: 10.1111/cea.14562. Epub 2024 Sep 20. Clin Exp Allergy. 2024. PMID: 39301832 Free PMC article.
Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate.
Bardelang P, Murray EJ, Blower I, Zandomeneghi S, Goode A, Hussain R, Kumari D, Siligardi G, Inoue K, Luckett J, Doutch J, Emsley J, Chan WC, Hill P, Williams P, Bonev BB. Bardelang P, et al. Among authors: emsley j. Front Chem. 2023 May 5;11:1113885. doi: 10.3389/fchem.2023.1113885. eCollection 2023. Front Chem. 2023. PMID: 37214482 Free PMC article.
Accuracy of point-of-care SARS-CoV-2 detection using buccal swabs in pediatric emergency departments.
Freedman SB, Kim K, Freire G, Kanngiesser A, Kam A, Doan Q, Wright B, Bhatt M, Berthelot S, Gravel J, Burstein B, Emsley J, Mater A, Porter R, Poonai N, Reddy D, Webster RJ, Goldfarb DM, Leifso K, Zemek R; Pediatric Emergency Research Canada (PERC) COVID Study Group. Freedman SB, et al. Among authors: emsley j. Microbiol Spectr. 2024 Oct 29;12(12):e0188424. doi: 10.1128/spectrum.01884-24. Online ahead of print. Microbiol Spectr. 2024. PMID: 39470284 Free PMC article.
Social Behaviors Associated with SARS-CoV-2 Test Positivity Among Children Evaluated in Canadian Emergency Departments, 2020 to 2022: A Cross-Sectional Survey Study.
Sumner M, Tarr GAM, Xie J, Mater A, Winston K, Gravel J, Poonai N, Burstein B, Berthelot S, Zemek R, Porter R, Wright B, Kam A, Emsley J, Sabhaney V, Beer D, Freire G, Moffatt A, Freedman SB; Pediatric Emergency Research Canada. Sumner M, et al. Among authors: emsley j. Acad Pediatr. 2024 Aug 30:S1876-2859(24)00333-4. doi: 10.1016/j.acap.2024.08.016. Online ahead of print. Acad Pediatr. 2024. PMID: 39216802 Free article.
183 results