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Page 1
A universal deep-learning model for zinc finger design enables transcription factor reprogramming.
Ichikawa DM, Abdin O, Alerasool N, Kogenaru M, Mueller AL, Wen H, Giganti DO, Goldberg GW, Adams S, Spencer JM, Razavi R, Nim S, Zheng H, Gionco C, Clark FT, Strokach A, Hughes TR, Lionnet T, Taipale M, Kim PM, Noyes MB. Ichikawa DM, et al. Among authors: goldberg gw. Nat Biotechnol. 2023 Aug;41(8):1117-1129. doi: 10.1038/s41587-022-01624-4. Epub 2023 Jan 26. Nat Biotechnol. 2023. PMID: 36702896 Free PMC article.
Manipulating the 3D organization of the largest synthetic yeast chromosome.
Zhang W, Lazar-Stefanita L, Yamashita H, Shen MJ, Mitchell LA, Kurasawa H, Lobzaev E, Fanfani V, Haase MAB, Sun X, Jiang Q, Goldberg GW, Ichikawa DM, Lauer SL, McCulloch LH, Easo N, Lin SJ, Camellato BR, Zhu Y, Cai J, Xu Z, Zhao Y, Sacasa M; Build-A-Genome Class; Noyes MB, Bader JS, Deutsch S, Stracquadanio G, Aizawa Y, Dai J, Boeke JD. Zhang W, et al. Among authors: goldberg gw. Mol Cell. 2023 Dec 7;83(23):4424-4437.e5. doi: 10.1016/j.molcel.2023.10.015. Epub 2023 Nov 8. Mol Cell. 2023. PMID: 37944526 Free article.
Engineered transcription-associated Cas9 targeting in eukaryotic cells.
Goldberg GW, Kogenaru M, Keegan S, Haase MAB, Kagermazova L, Arias MA, Onyebeke K, Adams S, Beyer DK, Fenyö D, Noyes MB, Boeke JD. Goldberg GW, et al. Nat Commun. 2024 Nov 27;15(1):10287. doi: 10.1038/s41467-024-54629-9. Nat Commun. 2024. PMID: 39604381 Free PMC article.
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials.
Bikard D, Euler CW, Jiang W, Nussenzweig PM, Goldberg GW, Duportet X, Fischetti VA, Marraffini LA. Bikard D, et al. Among authors: goldberg gw. Nat Biotechnol. 2014 Nov;32(11):1146-50. doi: 10.1038/nbt.3043. Epub 2014 Oct 5. Nat Biotechnol. 2014. PMID: 25282355 Free PMC article.
Cas9 specifies functional viral targets during CRISPR-Cas adaptation.
Heler R, Samai P, Modell JW, Weiner C, Goldberg GW, Bikard D, Marraffini LA. Heler R, et al. Among authors: goldberg gw. Nature. 2015 Mar 12;519(7542):199-202. doi: 10.1038/nature14245. Epub 2015 Feb 18. Nature. 2015. PMID: 25707807 Free PMC article.
12 results