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In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice.
Bouffi C, Wikenheiser-Brokamp KA, Chaturvedi P, Sundaram N, Goddard GR, Wunderlich M, Brown NE, Staab JF, Latanich R, Zachos NC, Holloway EM, Mahe MM, Poling HM, Vales S, Fisher GW, Spence JR, Mulloy JC, Zorn AM, Wells JM, Helmrath MA. Bouffi C, et al. Among authors: mahe mm. Nat Biotechnol. 2023 Jun;41(6):824-831. doi: 10.1038/s41587-022-01558-x. Epub 2023 Jan 26. Nat Biotechnol. 2023. PMID: 36702898 Free PMC article.
Intestinal stem cells remain viable after prolonged tissue storage.
Fuller MK, Faulk DM, Sundaram N, Mahe MM, Stout KM, von Furstenberg RJ, Smith BJ, McNaughton KK, Shroyer NF, Helmrath MA, Henning SJ. Fuller MK, et al. Among authors: mahe mm. Cell Tissue Res. 2013 Nov;354(2):441-50. doi: 10.1007/s00441-013-1674-y. Epub 2013 Jul 3. Cell Tissue Res. 2013. PMID: 23820734 Free PMC article.
Establishment of Gastrointestinal Epithelial Organoids.
Mahe MM, Aihara E, Schumacher MA, Zavros Y, Montrose MH, Helmrath MA, Sato T, Shroyer NF. Mahe MM, et al. Curr Protoc Mouse Biol. 2013 Dec 19;3(4):217-40. doi: 10.1002/9780470942390.mo130179. Curr Protoc Mouse Biol. 2013. PMID: 25105065 Free PMC article.
An in vivo model of human small intestine using pluripotent stem cells.
Watson CL, Mahe MM, Múnera J, Howell JC, Sundaram N, Poling HM, Schweitzer JI, Vallance JE, Mayhew CN, Sun Y, Grabowski G, Finkbeiner SR, Spence JR, Shroyer NF, Wells JM, Helmrath MA. Watson CL, et al. Among authors: mahe mm. Nat Med. 2014 Nov;20(11):1310-4. doi: 10.1038/nm.3737. Epub 2014 Oct 19. Nat Med. 2014. PMID: 25326803 Free PMC article.
CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation.
Bertaux-Skeirik N, Feng R, Schumacher MA, Li J, Mahe MM, Engevik AC, Javier JE, Peek RM Jr, Ottemann K, Orian-Rousseau V, Boivin GP, Helmrath MA, Zavros Y. Bertaux-Skeirik N, et al. Among authors: mahe mm. PLoS Pathog. 2015 Feb 6;11(2):e1004663. doi: 10.1371/journal.ppat.1004663. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25658601 Free PMC article.
Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo.
Finkbeiner SR, Hill DR, Altheim CH, Dedhia PH, Taylor MJ, Tsai YH, Chin AM, Mahe MM, Watson CL, Freeman JJ, Nattiv R, Thomson M, Klein OD, Shroyer NF, Helmrath MA, Teitelbaum DH, Dempsey PJ, Spence JR. Finkbeiner SR, et al. Among authors: mahe mm. Stem Cell Reports. 2015 Jun 3;4(6):1140-55. doi: 10.1016/j.stemcr.2015.04.010. Online ahead of print. Stem Cell Reports. 2015. PMID: 26050928 Free PMC article.
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.
Workman MJ, Mahe MM, Trisno S, Poling HM, Watson CL, Sundaram N, Chang CF, Schiesser J, Aubert P, Stanley EG, Elefanty AG, Miyaoka Y, Mandegar MA, Conklin BR, Neunlist M, Brugmann SA, Helmrath MA, Wells JM. Workman MJ, et al. Among authors: mahe mm. Nat Med. 2017 Jan;23(1):49-59. doi: 10.1038/nm.4233. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869805 Free PMC article.
The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach.
Engevik AC, Feng R, Choi E, White S, Bertaux-Skeirik N, Li J, Mahe MM, Aihara E, Yang L, DiPasquale B, Oh S, Engevik KA, Giraud AS, Montrose MH, Medvedovic M, Helmrath MA, Goldenring JR, Zavros Y. Engevik AC, et al. Among authors: mahe mm. Cell Mol Gastroenterol Hepatol. 2016 May 17;2(5):605-624. doi: 10.1016/j.jcmgh.2016.05.004. eCollection 2016 Sep. Cell Mol Gastroenterol Hepatol. 2016. PMID: 27990460 Free PMC article.
54 results