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Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases.
Yuan K, Longchamps RJ, Pardiñas AF, Yu M, Chen TT, Lin SC, Chen Y, Lam M, Liu R, Xia Y, Guo Z, Shi W, Shen C; Schizophrenia Workgroup of Psychiatric Genomics Consortium; Daly MJ, Neale BM, Feng YA, Lin YF, Chen CY, O'Donovan M, Ge T, Huang H. Yuan K, et al. Among authors: yu m. medRxiv [Preprint]. 2023 Jul 9:2023.01.07.23284293. doi: 10.1101/2023.01.07.23284293. medRxiv. 2023. Update in: Nat Genet. 2024 Sep;56(9):1841-1850. doi: 10.1038/s41588-024-01870-z PMID: 36711496 Free PMC article. Updated. Preprint.
Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits.
Chen CY, Chen TT, Anne Feng YC, Yu M, Lin SC, Longchamps RJ, Wang SH, Hsu YH, Yang HI, Kuo PH, Daly MJ, Chen WJ, Huang H, Ge T, Lin YF. Chen CY, et al. Among authors: yu m. Cell Genom. 2024 Sep 11;4(9):100640. doi: 10.1016/j.xgen.2024.100640. Epub 2024 Aug 15. Cell Genom. 2024. PMID: 39147635 Free PMC article. No abstract available.
Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases.
Yuan K, Longchamps RJ, Pardiñas AF, Yu M, Chen TT, Lin SC, Chen Y, Lam M, Liu R, Xia Y, Guo Z, Shi W, Shen C; Schizophrenia Workgroup of Psychiatric Genomics Consortium; Daly MJ, Neale BM, Feng YA, Lin YF, Chen CY, O'Donovan MC, Ge T, Huang H. Yuan K, et al. Among authors: yu m. Nat Genet. 2024 Sep;56(9):1841-1850. doi: 10.1038/s41588-024-01870-z. Epub 2024 Aug 26. Nat Genet. 2024. PMID: 39187616
A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner.
Boltz TA, Chu BB, Liao C, Sealock JM, Ye R, Majara L, Fu JM, Service S, Zhan L, Medland SE, Chapman SB, Rubinacci S, DeFelice M, Grimsby JL, Abebe T, Alemayehu M, Ashaba FK, Atkinson EG, Bigdeli T, Bradway AB, Brand H, Chibnik LB, Fekadu A, Gatzen M, Gelaye B, Gichuru S, Gildea ML, Hill TC, Huang H, Hubbard KM, Injera WE, James R, Joloba M, Kachulis C, Kalmbach PR, Kamulegeya R, Kigen G, Kim S, Koen N, Kwobah EK, Kyebuzibwa J, Lee S, Lennon NJ, Lind PA, Lopera-Maya EA, Makale J, Mangul S, McMahon J, Mowlem P, Musinguzi H, Mwema RM, Nakasujja N, Newman CP, Nkambule LL, O'Neil CR, Olivares AM, Olsen CM, Ongeri L, Parsa SJ, Pretorius A, Ramesar R, Reagan FL, Sabatti C, Schneider JA, Shiferaw W, Stevenson A, Stricker E, Stroud RE 2nd, Tang J, Whiteman D, Yohannes MT, Yu M, Yuan K; NeuroGAP-Psychosis; Akena D, Atwoli L, Kariuki SM, Koenen KC, Newton CRJC, Stein DJ, Teferra S, Zingela Z, Pato CN, Pato MT, Lopez-Jaramillo C, Freimer N, Ophoff RA, Olde Loohuis LM, Talkowski ME, Neale BM, Howrigan DP, Martin AR. Boltz TA, et al. Among authors: yu m. bioRxiv [Preprint]. 2024 Sep 8:2024.09.06.611689. doi: 10.1101/2024.09.06.611689. bioRxiv. 2024. PMID: 39282356 Free PMC article. Preprint.
Cystic fibrosis risk variants confer protection against inflammatory bowel disease.
Yu M, Zhang Q, Yuan K, Sazonovs A, Stevens C, Fachal L; International Inflammatory Bowel Disease Genetics Consortium; Anderson CA, Daly MJ, Huang H. Yu M, et al. medRxiv [Preprint]. 2024 Dec 5:2024.12.02.24318364. doi: 10.1101/2024.12.02.24318364. medRxiv. 2024. PMID: 39677473 Free PMC article. Preprint.
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