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Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma.
Huang KC, Gomes C, Shiga Y, Belforte N, VanderWall KB, Lavekar SS, Fligor CM, Harkin J, Di Polo A, Meyer JS. Huang KC, et al. bioRxiv [Preprint]. 2023 Jan 4:2023.01.04.522687. doi: 10.1101/2023.01.04.522687. bioRxiv. 2023. Update in: Acta Neuropathol Commun. 2024 Oct 18;12(1):164. doi: 10.1186/s40478-024-01872-2 PMID: 36711831 Free PMC article. Updated. Preprint.
Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids.
VanderWall KB, Huang KC, Pan Y, Lavekar SS, Fligor CM, Allsop AR, Lentsch KA, Dang P, Zhang C, Tseng HC, Cummins TR, Meyer JS. VanderWall KB, et al. Among authors: huang kc. Stem Cell Reports. 2020 Jul 14;15(1):52-66. doi: 10.1016/j.stemcr.2020.05.009. Epub 2020 Jun 11. Stem Cell Reports. 2020. PMID: 32531194 Free PMC article.
Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium.
Soucy JR, Aguzzi EA, Cho J, Gilhooley MJ, Keuthan C, Luo Z, Monavarfeshani A, Saleem MA, Wang XW, Wohlschlegel J; RReSTORe Consortium; Baranov P, Di Polo A, Fortune B, Gokoffski KK, Goldberg JL, Guido W, Kolodkin AL, Mason CA, Ou Y, Reh TA, Ross AG, Samuels BC, Welsbie D, Zack DJ, Johnson TV. Soucy JR, et al. Mol Neurodegener. 2023 Sep 21;18(1):64. doi: 10.1186/s13024-023-00655-y. Mol Neurodegener. 2023. PMID: 37735444 Free PMC article. Review.
A highly reproducible and efficient method for retinal organoid differentiation from human pluripotent stem cells.
Harkin J, Peña KH, Gomes C, Hernandez M, Lavekar SS, So K, Lentsch K, Feder EM, Morrow S, Huang KC, Tutrow KD, Morris A, Zhang C, Meyer JS. Harkin J, et al. Among authors: huang kc. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2317285121. doi: 10.1073/pnas.2317285121. Epub 2024 Jun 13. Proc Natl Acad Sci U S A. 2024. PMID: 38870053 Free PMC article.
1,051 results