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Human Astrocytes Synchronize Neural Organoid Networks.
Patel MD, Lavekar SS, Jaisalmeria R, Oji S, Jayasi J, Cvetkovic C, Krencik R. Patel MD, et al. Among authors: lavekar ss. bioRxiv [Preprint]. 2024 Oct 17:2024.10.17.618921. doi: 10.1101/2024.10.17.618921. bioRxiv. 2024. PMID: 39464076 Free PMC article. Preprint.
Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction.
Huang KC, Gomes C, Shiga Y, Belforte N, VanderWall KB, Lavekar SS, Fligor CM, Harkin J, Hetzer SM, Patil SV, Di Polo A, Meyer JS. Huang KC, et al. Among authors: lavekar ss. Acta Neuropathol Commun. 2024 Oct 18;12(1):164. doi: 10.1186/s40478-024-01872-2. Acta Neuropathol Commun. 2024. PMID: 39425218 Free PMC article.
A highly reproducible and efficient method for retinal organoid differentiation from human pluripotent stem cells.
Harkin J, Peña KH, Gomes C, Hernandez M, Lavekar SS, So K, Lentsch K, Feder EM, Morrow S, Huang KC, Tutrow KD, Morris A, Zhang C, Meyer JS. Harkin J, et al. Among authors: lavekar ss. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2317285121. doi: 10.1073/pnas.2317285121. Epub 2024 Jun 13. Proc Natl Acad Sci U S A. 2024. PMID: 38870053 Free PMC article.
Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma.
Huang KC, Gomes C, Shiga Y, Belforte N, VanderWall KB, Lavekar SS, Fligor CM, Harkin J, Di Polo A, Meyer JS. Huang KC, et al. Among authors: lavekar ss. bioRxiv [Preprint]. 2023 Jan 4:2023.01.04.522687. doi: 10.1101/2023.01.04.522687. bioRxiv. 2023. Update in: Acta Neuropathol Commun. 2024 Oct 18;12(1):164. doi: 10.1186/s40478-024-01872-2 PMID: 36711831 Free PMC article. Updated. Preprint.
12 results