Kume T - Search Results

1

Chronic Treatment with Aβ42 with a Toxic Conformer and LPS Induces Inflammatory Responses in BV-2 Microglia with Dysregulation of Hypoxia-Inducible Factor Expression.

Maki T, Sawahata M, Uta D, Irie K, Kume T. Maki T, et al. Among authors: kume t. Biol Pharm Bull. 2023;46(2):359-363. doi: 10.1248/bpb.b22-00855. Biol Pharm Bull. 2023. PMID: 36724966 Free article.

2

Endogenous factors regulating neuronal death induced by radical stress.

Kume T, Katsuki H, Akaike A. Kume T, et al. Biol Pharm Bull. 2004 Jul;27(7):964-7. doi: 10.1248/bpb.27.964. Biol Pharm Bull. 2004. PMID: 15256723 Free article. Review.

3

E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity.

Suzuki T, Murakami K, Izuo N, Kume T, Akaike A, Nagata T, Nishizaki T, Tomiyama T, Takuma H, Mori H, Irie K. Suzuki T, et al. Among authors: kume t. Int J Alzheimers Dis. 2010 Dec 19;2011:431320. doi: 10.4061/2011/431320. Int J Alzheimers Dis. 2010. PMID: 21234376 Free PMC article.

4

Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis).

Izumi Y, Matsumura A, Wakita S, Akagi K, Fukuda H, Kume T, Irie K, Takada-Takatori Y, Sugimoto H, Hashimoto T, Akaike A. Izumi Y, et al. Among authors: kume t. Free Radic Biol Med. 2012 Aug 15;53(4):669-79. doi: 10.1016/j.freeradbiomed.2012.06.021. Epub 2012 Jun 27. Free Radic Biol Med. 2012. PMID: 22749808 Free article.

5

Toxicity in rat primary neurons through the cellular oxidative stress induced by the turn formation at positions 22 and 23 of Aβ42.

Izuo N, Kume T, Sato M, Murakami K, Irie K, Izumi Y, Akaike A. Izuo N, et al. Among authors: kume t. ACS Chem Neurosci. 2012 Sep 19;3(9):674-81. doi: 10.1021/cn300033k. Epub 2012 Jun 6. ACS Chem Neurosci. 2012. PMID: 23019494 Free PMC article.

6

Non-toxic conformer of amyloid β may suppress amyloid β-induced toxicity in rat primary neurons: implications for a novel therapeutic strategy for Alzheimer's disease.

Izuo N, Murakami K, Sato M, Iwasaki M, Izumi Y, Shimizu T, Akaike A, Irie K, Kume T. Izuo N, et al. Among authors: kume t. Biochem Biophys Res Commun. 2013 Aug 16;438(1):1-5. doi: 10.1016/j.bbrc.2013.05.106. Epub 2013 Jun 4. Biochem Biophys Res Commun. 2013. PMID: 23747423

7

Neuroprotective effects of curcumin and highly bioavailable curcumin on oxidative stress induced by sodium nitroprusside in rat striatal cell culture.

Nazari QA, Kume T, Izuo N, Takada-Takatori Y, Imaizumi A, Hashimoto T, Izumi Y, Akaike A. Nazari QA, et al. Among authors: kume t. Biol Pharm Bull. 2013;36(8):1356-62. doi: 10.1248/bpb.b13-00300. Biol Pharm Bull. 2013. PMID: 23902979 Free article.

8

Protective Effect of Dimethyl Fumarate on an Oxidative Stress Model Induced by Sodium Nitroprusside in Mice.

Kume T, Suenaga A, Izumi Y, Akaike A. Kume T, et al. Biol Pharm Bull. 2016;39(6):1055-9. doi: 10.1248/bpb.b16-00134. Biol Pharm Bull. 2016. PMID: 27251510 Free article.

9

Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer's disease diagnosis.

Murakami K, Tokuda M, Suzuki T, Irie Y, Hanaki M, Izuo N, Monobe Y, Akagi K, Ishii R, Tatebe H, Tokuda T, Maeda M, Kume T, Shimizu T, Irie K. Murakami K, et al. Among authors: kume t. Sci Rep. 2016 Jul 4;6:29038. doi: 10.1038/srep29038. Sci Rep. 2016. PMID: 27374357 Free PMC article.

10

Therapeutic Potential of the Activators of the Nuclear Factor Erythroid 2-Related Factor 2-Antioxidant Response Element Pathway in Brain Disorders.

Kume T. Kume T. Biol Pharm Bull. 2017;40(5):553-556. doi: 10.1248/bpb.b17-00091. Biol Pharm Bull. 2017. PMID: 28458340 Free article. Review.

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