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Page 1
Macrophage Galactose Lectin Contributes to the Regulation of FVIII (Factor VIII) Clearance in Mice-Brief Report.
Ward SE, Guest T, Byrne C, Lopes P, O'Sullivan JM, Doherty D, O'Connell D, Gutierrez Llaneza S, Chion A, Fazavana J, Fallon PG, Preston RJS, Johnsen JM, Pipe SW, Turecek PL, O'Donnell JS; iPATH Study Group. Ward SE, et al. Among authors: chion a. Arterioscler Thromb Vasc Biol. 2023 Apr;43(4):540-546. doi: 10.1161/ATVBAHA.122.317807. Epub 2023 Feb 2. Arterioscler Thromb Vasc Biol. 2023. PMID: 36727518 Free PMC article.
von Willebrand factor links primary hemostasis to innate immunity.
Drakeford C, Aguila S, Roche F, Hokamp K, Fazavana J, Cervantes MP, Curtis AM, Hawerkamp HC, Dhami SPS, Charles-Messance H, Hackett EE, Chion A, Ward S, Ahmad A, Schoen I, Breen E, Keane J, Murphy R, Preston RJS, O'Sullivan JM, Sheedy FJ, Fallon P, O'Donnell JS. Drakeford C, et al. Among authors: chion a. Nat Commun. 2022 Nov 3;13(1):6320. doi: 10.1038/s41467-022-33796-7. Nat Commun. 2022. PMID: 36329021 Free PMC article.
R1205H (Vicenza) causes conformational changes in the von Willebrand factor D'D3 domains and enhances von Willebrand factor binding to clearance receptors LRP1 and SR-AI.
Atiq F, Rawley O, O'Sullivan JM, Özbil M, Doherty D, Cooke N, Terraube V, Chion A, Amin A, Hulshof AM, Baci B, Byrne C, Aburawi HE, Lillicrap D, O'Donnell JS. Atiq F, et al. Among authors: chion a. J Thromb Haemost. 2024 Oct;22(10):2752-2760. doi: 10.1016/j.jtha.2024.06.023. Epub 2024 Jul 10. J Thromb Haemost. 2024. PMID: 38996914 Free article.
Increased galactose expression and enhanced clearance in patients with low von Willebrand factor.
Aguila S, Lavin M, Dalton N, Patmore S, Chion A, Trahan GD, Jones KL, Keenan C, Brophy TM, O'Connell NM, Ryan K, Byrne M, Nolan M, Patel A, Preston RJS, James P, Di Paola J, O'Sullivan JM, O'Donnell JS. Aguila S, et al. Among authors: chion a. Blood. 2019 Apr 4;133(14):1585-1596. doi: 10.1182/blood-2018-09-874636. Epub 2019 Feb 15. Blood. 2019. PMID: 30770394 Free article.
21 results