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The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins.
Rosenberg EM Jr, Jian X, Soubias O, Yoon HY, Yadav MP, Hammoudeh S, Pallikkuth S, Akpan I, Chen PW, Maity TK, Jenkins LM, Yohe ME, Byrd RA, Randazzo PA. Rosenberg EM Jr, et al. Among authors: randazzo pa. J Biol Chem. 2023 Mar;299(3):102992. doi: 10.1016/j.jbc.2023.102992. Epub 2023 Feb 8. J Biol Chem. 2023. PMID: 36758799 Free PMC article.
Identification of a new Pyk2 target protein with Arf-GAP activity.
Andreev J, Simon JP, Sabatini DD, Kam J, Plowman G, Randazzo PA, Schlessinger J. Andreev J, et al. Among authors: randazzo pa. Mol Cell Biol. 1999 Mar;19(3):2338-50. doi: 10.1128/MCB.19.3.2338. Mol Cell Biol. 1999. PMID: 10022920 Free PMC article.
133 results