Singh S - Search Results

1

Rapid profiling of DNA replication dynamics using mass spectrometry-based analysis of nascent DNA.

Ashour ME, Byrum AK, Meroni A, Xia J, Singh S, Galletto R, Rosenberg SM, Vindigni A, Mosammaparast N. Ashour ME, et al. Among authors: singh s. J Cell Biol. 2023 Apr 3;222(4):e202207121. doi: 10.1083/jcb.202207121. Epub 2023 Feb 16. J Cell Biol. 2023. PMID: 36795402 Free PMC article.

2

A Monomer of Pif1 Unwinds Double-Stranded DNA and It Is Regulated by the Nature of the Non-Translocating Strand at the 3'-End.

Singh SP, Koc KN, Stodola JL, Galletto R. Singh SP, et al. J Mol Biol. 2016 Mar 27;428(6):1053-1067. doi: 10.1016/j.jmb.2016.02.017. Epub 2016 Feb 22. J Mol Biol. 2016. PMID: 26908222 Free PMC article.

3

Pif1 removes a Rap1-dependent barrier to the strand displacement activity of DNA polymerase δ.

Koc KN, Singh SP, Stodola JL, Burgers PM, Galletto R. Koc KN, et al. Nucleic Acids Res. 2016 May 5;44(8):3811-9. doi: 10.1093/nar/gkw181. Epub 2016 Mar 21. Nucleic Acids Res. 2016. PMID: 27001517 Free PMC article.

4

The mitochondrial single-stranded DNA binding protein from S. cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers.

Singh SP, Kukshal V, De Bona P, Antony E, Galletto R. Singh SP, et al. Nucleic Acids Res. 2018 Aug 21;46(14):7193-7205. doi: 10.1093/nar/gky530. Nucleic Acids Res. 2018. PMID: 29931186 Free PMC article.

5

The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity.

Geronimo CL, Singh SP, Galletto R, Zakian VA. Geronimo CL, et al. Nucleic Acids Res. 2018 Sep 19;46(16):8357-8370. doi: 10.1093/nar/gky655. Nucleic Acids Res. 2018. PMID: 30239884 Free PMC article.

6

Pif1 is essential for efficient replisome progression through lagging strand G-quadruplex DNA secondary structures.

Dahan D, Tsirkas I, Dovrat D, Sparks MA, Singh SP, Galletto R, Aharoni A. Dahan D, et al. Nucleic Acids Res. 2018 Dec 14;46(22):11847-11857. doi: 10.1093/nar/gky1065. Nucleic Acids Res. 2018. PMID: 30395308 Free PMC article.

7

A stable tetramer is not the only oligomeric state that mitochondrial single-stranded DNA binding proteins can adopt.

Singh SP, Kukshal V, Galletto R. Singh SP, et al. J Biol Chem. 2019 Mar 15;294(11):4137-4144. doi: 10.1074/jbc.RA118.007048. Epub 2019 Jan 7. J Biol Chem. 2019. PMID: 30617184 Free PMC article.

8

Complementary roles of Pif1 helicase and single stranded DNA binding proteins in stimulating DNA replication through G-quadruplexes.

Sparks MA, Singh SP, Burgers PM, Galletto R. Sparks MA, et al. Nucleic Acids Res. 2019 Sep 19;47(16):8595-8605. doi: 10.1093/nar/gkz608. Nucleic Acids Res. 2019. PMID: 31340040 Free PMC article.

9

Branched unwinding mechanism of the Pif1 family of DNA helicases.

Singh SP, Soranno A, Sparks MA, Galletto R. Singh SP, et al. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24533-24541. doi: 10.1073/pnas.1915654116. Epub 2019 Nov 19. Proc Natl Acad Sci U S A. 2019. PMID: 31744872 Free PMC article.

10

Rrm3 and Pif1 division of labor during replication through leading and lagging strand G-quadruplex.

Varon M, Dovrat D, Heuzé J, Tsirkas I, Singh SP, Pasero P, Galletto R, Aharoni A. Varon M, et al. Nucleic Acids Res. 2024 Feb 28;52(4):1753-1762. doi: 10.1093/nar/gkad1205. Nucleic Acids Res. 2024. PMID: 38117984 Free PMC article.

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